News

July 3, 2015
Wissenschaftlern über die Schulter geschaut » more

June 29, 2015
Stellungnahme des Beutenberg Campus / FLI zu den Überfällen auf indische Studierende in Jena-Lobeda » more

April 24, 2015
Neugierige Schüler » more

  » Overview News


Press Releases

July 3, 2015
Forschen in ausgezeichnetem Ambiente - BDA verleiht Architektur-Preis „Eins zu Eins“ an FLI-Laborneubau » more

July 1, 2015
Advantage: Youth – Fin Regenerative Capability Abates During Aging » more

June 29, 2015
Lean but sated: Molecular Switch for a Healthy Metabolism discovered » more

  » Overview Press Releases


 

Our Mission

Human ageing is a multifactorial process controlled by both environmental and genetic factors. Our mission is to understand the molecular mechanisms that underlie the ageing process and that lead to age-related diseases. We hope that eventually this knowledge can contribute to a more healthy ageing of people. The central question we are aiming at answering is

 

«What are the molecular mechanisms and genetic factors contributing to the evolution of cellular and organismal dysfunction during human aging?».

 


 

Recent Selected Publications


Age-dependent decline in fin regenerative capacity in the short-lived fish Nothobranchius furzeri
Wendler S, Hartmann N, Hoppe B, Englert C
Aging Cell. 2015 (epub ahead of print) [PubMed]

 

Deficiency in mTORC1-controlled C/EBPβ-mRNA translation improves metabolic health in mice
Zidek LM, Ackermann T, Hartleben G, Eichwald S, Kortman G, Kiehntopf M, Leutz A, Sonenberg N, Wang ZQ, von Maltzahn J, Müller C, Calkhoven CF
EMBO Rep. 2015 (epub ahead of print) [PubMed]

 

Stem Cells and Aging: What’s Next?
Artandi SE, Blau HM, de Haan G, Geiger H, Goodell MA, Jones L, Levine RL, Munoz-Canoves P, Rodewald HR, Wagers A, Wang ZQ, Yamashita Y
Cell Stem Cell 2015, 16, 578-581

 

From the bush to the bench: the annual Nothobranchius fishes as a new model system in biology
Cellerino A, Valenzano DR, Reichard M
Biol Rev. 2015 (epub ahead of print) [PubMed]

 

Wip1 deficiency impairs haematopoietic stem cell function via p53 and mTORC1 pathways
Chen Z, Yi W, Morita Y, Wang H, Cong Y, Liu JP, Xiao Z, Rudolph KL, Cheng T, Ju Z
Nat Commun. 2015, 6, 6808 [PubMed]

 

» Overview Publications