Ausgewählte Publikationen
(letzter 5-Jahres-Impact-Faktor größer 7; in chronologischer Reihenfolge)

 

Disrupted-in-schizophrenia 1 (DISC1) is necessary for the correct migration of cortical interneurons

Steinecke A, Gampe C, Valkova C, Kaether C, Bolz J

J Neurosci 2012, 32, 738-745 [PubMed]


Structural basis of β-amyloid-dependent synaptic dysfunctions

Haupt C, Leppert J, Rönicke R, Meinhardt J, Yadav JK, Ramachandran R, Ohlenschläger O, Reymann KG, Görlach M, Fändrich M.

Angew Chem Int Ed Engl. 2012, 51, 1576-1579 [PubMed]


A distinct response to endogenous DNA damage in the development of Nbs1-deficient cortical neurons

Li R, Yang YG, Gao Y, Wang ZQ, Tong WM

Cell Res. 2012 (epub ahead of print) [PubMed]


Mapping of quantitative trait loci controlling lifespan in the short-lived fish Nothobranchius furzeri – a new vertebrate model for age research

Kirschner J, Weber D, Neuschl C, Franke A, Böttger M, Zielke L, Powalsky E, Groth M, Shagin D, Petzold A, Hartmann N, Englert C, Brockmann GA, Platzer M, Cellerino A, Reichwald K

Aging Cell 2012 (epub ehead of print) [PubMed]


Adult neurogenesis in the short-lived teleost Nothobranchius furzeri: localization of neurogenic niches, molecular characterization and effects of aging

Tozzini ET, Baumgart M, Battistoni G, Cellerino A

Aging Cell. 2012 (epub ehead of print) [PubMed]


Heterozygous mutations causing partial prohormone convertase 1 deficiency contribute to human obesity

Creemers J, Choquet H, Stijnen P, Vatin V, Pigeyre M, Beckers S, Meulemans S, Than ME, Yengo L, Tauber M, Balkau B, Elliott P, Jarvelin M-R, Van Hul W, Van Gaal L, Hoberl F, Pattoul F, Froguel P, Meyre D

Diabetes 2012, 61, 383-390 [PubMed]


Colony-stimulating factor-1 mediates macrophage-related neural damage in a model for Charcot-Marie-Tooth disease type 1X

Groh J, Weis J, Zieger H, Stanley E, Heuer H, Martini R

Brain 2012, 135, 88-104 [PubMed]


Glucocorticoid receptor dimerization is required for survival in septic shock via suppression of interleukin-1 in macrophages

Kleiman A, Hübner S, Rodriguez Parkitna JM, Neumann A, Hofer S, Weigand MA, Bauer M, Schmid W, Schütz G, Libert C, Reichardt HM, Tuckermann JP

FASEB J. 2012, 26, 722-729 [PubMed]


Glucocorticoid therapy of antigen-induced arthritis depends on the dimerized glucocorticoid receptor in T cells

Baschant U, Frappart L, Rauchhaus U, Bruns L, Reichardt HM, Kamradt T, Bräuer R, Tuckermann JP

Proc Natl Acad Sci USA. 2011, 108, 19317-19322 [PubMed]

Evaluated by "Faculty of 1000"

MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1Cdc25 pathway

Gruber R, Zhou Z, Sukchev M, Joerss T, Frappart PO, Wang ZQ

Nat Cell Biol. 2011, 13, 1325-1334 [PubMed]


Molecular control of systemic bile acid homeostasis by the liver glucocorticoid receptor

Rose AJ, Díaz MB, Reimann A, Klement J, Walcher T, Krones-Herzig A, Strobel O, Werner J, Peters A, Kleyman A, Tuckermann JP, Vegiopoulos A, Herzig S

Cell Metab. 2011, 14, 123-130 [PubMed]


Requirement for DNA ligase IV during embryonic neuronal development

Gatz SA, Ju L, Gruber R, Hoffmann E, Carr AM, Wang ZQ, Liu C, Jeggo PA

J Neurosci. 2011, 31, 10088-10100 [PubMed]


Phylogeny-wide analysis of social amoeba genomes highlights ancient origins for complex intercellular communication

Heidel AJ, Lawal HM, Felder M, Schilde C, Helps NR, Tunggal B, Rivero F, John U, Schleicher M, Eichinger L, Platzer M, Noegel AA, Schaap P, Glöckner G

Genome Res. 2011, 21, 1882-1891 [PubMed]


Premitotic assembly of human CENPs -T and -W switches centromeric chromatin to a mitotic state

Prendergast L, van Vuuren C, Kaczmarczyk A, Doering V, Hellwig D, Quinn N, Hoischen C, Diekmann S, Sullivan KF

PLoS Biol. 2011, 9, e1001077 [PubMed]


Mitochondrial DNA copy number and function decrease with age in the short-lived fish Nothobranchius furzeri

Hartmann N, Reichwald K, Wittig I, Dröse S, Schmeisser S, Lück C, Hahn C, Graf M, Gausmann U, Terzibasi E, Cellerino A, Ristow M, Brandt U, Platzer M, Englert C

Aging Cell. 2011, 10, 824-831 [PubMed]


RelA and RelB transcription factors in distinct thymocyte populations control lymphotoxin-dependent interleukin-17 production in γδ T cells

Powolny-Budnicka I, Riemann M, Tänzer S, Schmid RM, Hehlgans T, Weih F

Immunity. 2011, 34, 364-374 [PubMed]


Segrosome assembly at the pliable parH centromere

Wu M, Zampini M, Bussiek M, Hoischen C, Diekmann S, Hayes F

Nucleic Acids Res. 2011, 39, 5082-5097 [PubMed]


Revealing the position of the substrate in nickel superoxide dismutase: a model study

Tietze D, Voigt S, Mollenhauer D, Tischler M, Imhof D, Gutmann T, González L, Ohlenschläger O, Breitzke H, Görlach M, Buntkowsky G

Angew Chem Int Ed Engl. 2011, 50, 2946-2950 [PubMed]


Serine 312 phosphorylation is dispensable for wild-type p53 functions in vivo

Lee MK, Tong WM, Wang ZQ, Sabapathy K

Cell Death Differ. 2011, 18, 214-221 [PubMed]


Identification of adult nephron progenitors capable of kidney regeneration in zebrafish

Diep CQ, Ma D, Deo RC, Holm TM, Naylor RW, Arora N, Wingert RA, Bollig F, Djordjevic G, Lichman B, Zhu H, Ikenaga T, Ono F, Englert C, Cowan CA, Hukriede NA, Handin RI, Davidson AJ

Nature 2011, 470, 95-100 [PubMed]


Comparative and functional genomics provide insights into the pathogenicity of dermatophytic fungi

Burmester A*, Shelest E*, Glöckner G*, Heddergott C*, Schindler S, Staib P, Heidel A, Felder M, Petzold A, Szafranski K, Feuermann M, Pedruzzi I, Priebe S, Groth M, Winkler R, Li W, Kniemeyer O, Schroeckh V, Hertweck C, Hube B, White TC, Platzer M, Guthke R, Heitman J, Wöstemeyer J, Zipfel PF, Monod M, Brakhage AA

Genome Biol. 2011, 12, R7 (*equal contribution) [PubMed]


An anti-inflammatory selective glucocorticoid receptor modulator preserves osteoblast differentiation

Rauch A*, Gossye V*, Bracke D, Gevaert E, Jacques P, Van Beneden K, Vandooren B, Rauner M, Hofbauer LC, Haegeman G, Elewaut D, Tuckermann JP**, De Bosscher K**

FASEB J. 2011, 25, 1323-1332. (*,**equal contribution) [PubMed]


Endosymbiotic gene transfer and transcriptional regulation of transferred genes in Paulinella chromatophora

Nowack EC, Vogel H, Groth M, Grossman AR, Melkonian M, Glöckner G

Mol Biol Evol. 2011, 28, 407-422 [PubMed]


Sorting receptor Rer1 controls surface expression of muscle acetylcholine receptors by ER retention of unassembled {alpha}-subunits

Valkova C*, Albrizio M*, Röder IV, Schwake M, Betto R, Rudolf R**, Kaether C**

Proc Natl Acad Sci USA 2011, 108, 621-625 (*,**equal contribution) [PubMed]


Unlocking the barley genome by chromosomal and comparative genomics

Mayer KF, Martis M, Hedley PE, Simková H, Liu H, Morris JA, Steuernagel B, Taudien S, Roessner S, Gundlach H, Kubaláková M, Suchánková P, Murat F, Felder M, Nussbaumer T, Graner A, Salse J, Endo T, Sakai H, Tanaka T, Itoh T, Sato K, Platzer M, Matsumoto T, Scholz U, Dolezel J, Waugh R, Stein N.

Plant Cell. 2011, 23, 1249-1263. [PubMed]


Frequent gene movement and pseudogene evolution is common to the large and complex genomes of wheat, barley, and their relatives

Wicker T, Mayer KF, Gundlach H, Martis M, Steuernagel B, Scholz U, Simková H, Kubaláková M, Choulet F, Taudien S, Platzer M, Feuillet C, Fahima T, Budak H, Dolezel J, Keller B, Stein N

Plant Cell. 2011, 23, 1706-1718 [PubMed]


Tetrameric organization of vertebrate centromeric nucleosomes

Dimitriadis EK, Weber C, Gill RK, Diekmann S, Dalal Y

Proc Natl Acad Sci USA. 2010, 107, 20317-20322 [PubMed]


Proteomic and functional analysis of the mitotic Drosophila centrosome

Müller H, Schmidt D, Steinbrink S, Mirgorodskaya E, Lehmann V, Habermann K, Dreher F, Gustavsson N, Kessler T, Lehrach H, Herwig R, Gobom J, Ploubidou A, Boutros M, Lange BMH

EMBO J 2010, 29, 3344-3357 [PubMed]


Thymus-derived glucocorticoids mediate androgen effects on thymocyte homeostasis

Chen Y, Qiao S, Tuckermann J, Okret S, Jondal M

FASEB J 2010, 24, 5043-5051 [PubMed]


WRN helicase unwinds Okazaki fragment-like hybrids in a reaction stimulated by the human DHX9 helicase

Chakraborty P, Grosse F

Nucleic Acids Res. 2010, 38, 4722-4730 [PubMed]


Merlin inhibits neurite outgrowth in the CNS

Schulz A, Geissler KJ, Kumar S, Leichsenring G, Morrison H*, Baader SL*

J Neurosci 2010, 30, 10177-10186 (*equal contribution) [PubMed]


Highly modular structure and ligand binding by conformational capture in a minimalistic riboswitch

Duchardt-Ferner E, Weigand JE, Ohlenschläger O, Schmidtke SR, Suess B, Wöhnert J

Angew Chem Int Ed Engl 2010, 49, 6216-6219 [PubMed]


ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import

Dormann D, Rodde R, Edbauer D, Bentmann E, Fischer I, Hruscha A, Than ME, Mackenzie IR, Capell A, Schmid B, Neumann M, Haass C

EMBO J 2010, 29, 2841-2857 [PubMed]

EMBO review

Glucocorticoids suppress bone formation by attenuating osteoblast differentiation via the monomeric glucocorticoid receptor

Rauch A, Seitz S, Baschant, U, Schilling AF, Illing A, Stride B, Kirilov M, Mandic V, Takacz A, Schmidt-Ullrich R, Ostermay S, Schinke T, Spanbroek R, Zaiss M, Angel PE, Lerner UH, David JP, Reichard HM, Amling M, Schütz G, Tuckermann J

Cell Metab 2010, 11, 517-531 [PubMed]


Processing of the NF-κB2 precursor p100 to p52 is critical for RANKL-induced osteoclast differentiation

Maruyama T, Fukushima H, Nakao K, Shin M, Yasuda H, Weih F, Doi T, Aoki K, Alles N, Ohya K, Hosokawa R, Jimi E

J Bone Miner Res 2010, 25, 1058-1067 [PubMed]


Cross talk between stimulated NF-κB and the tumor suppressor p53

Schneider G, Henrich A, Greiner G, Wolf V, Lovas A, Wieczorek M, Wagner T, Reichardt S, von Werder A, Schmid RM, Weih F, Heinzel T, Saur D, Krämer OH

Oncogene. 2010, 29, 2795-2806 [PubMed]


The pivotal role of the alternative NF-κB pathway in maintenance of basal bone homeostasis and osteoclastogenesis

Soysa NS, Alles N, Weih D, Lovas A, Mian AH, Shimokawa H, Yasuda H, Weih F, Jimi E, Ohya K, Aoki K

J Bone Miner Res. 2010, 25, 809-818 [PubMed]

Selected as "exceptional" by "Faculty of 1000"

Structure and biochemical analysis of the heparin-induced E1 dimer of the amyloid precursor protein

Dahms SO, Hoefgen S, Roeser D, Schlott B, Gührs KH, Than ME

Proc Natl Acad Sci USA. 2010, 107, 5381-5386 [PubMed]


Wt1 and retinoic acid signaling in the subcoelomic mesenchyme control the development of the pleuropericardial membranes and the sinus horns

Norden J, Grieskamp T, Lausch E, van Wijk B, van den Hoff MJB, Englert C, Petry M, Mommersteeg MTM, Christoffels VM, Niederreither K, Kispert A

Circ Res. 2010, 106, 1212-1220 [PubMed]


Mouse aorta smooth muscle cells differentiate into lymphoid tissue organizer-like cells upon combined TNFR1/LTβR NF-κB signaling

Lötzer K, Döpping S, Connert S, Gräbner R, Spanbroek R, Lemser B, Beer M, Hildner M, Hehlgans T, van der Wall M, Mebius RE, Lovas A, Randolph GJ, Weih F*, Habenicht AJR*

Arterioscler Thromb Vasc Biol. 2010, 30, 395-402 (*equal contribution) [PubMed]


Increased skeletal VEGF enhances β-catenin activity and results in excessively ossified bones

Maes C, Goossens S, Bartunkova S, Drogat B, Coenegrachts L, Stockmans I, Moermans K , Nyabi O, Haigh K , Naessens M, Haenebalcke L, Tuckermann JP, Tjwa M, Carmeliet P, Mandic V, David J-P, Behrens A, Nagy A, Carmeliet G, Haigh JJ

EMBO J. 2010, 29, 424-441 [PubMed]


Mechanism of amyloid plaque formation suggests an intracellular basis of Abeta pathogenicity

Friedrich RP, Tepper K, Rönicke R, Soom M, Westermann M, Reymann K, Kaether C, Fändrich M

Proc Natl Acad Sci USA. 2010, 107, 1942-1947 [PubMed]


Nucleolar retention of a translational C/EBPα isoform stimulates rDNA transcription and cell size

Müller C, Bremer A, Schreiber S, Eichwald S, Calkhoven CF

EMBO J. 2010, 29, 897-909 [PubMed]

EMBO Journal .pdf


C/EBPβΔuORFmice - a genetic model for uORF-mediated translational control in mammals

Wethmar K, Begay V, Smink JJ, Zaragoza K, Wiesenthal V, Dörken B, Calkhoven CF, Leutz A

Genes Dev. 2010, 24, 15-20 [PubMed]


Alpha2-macroglobulin inhibits the malignant properties of astrocytoma cells by impeding beta-catenin signaling

Lindner I, Hemdan NY, Buchold M, Huse K, Bigl M, Oerlecke I, Ricken A, Gaunitz F, Sack U, Naumann A, Hollborn M, Thal D, Gebhardt R, Birkenmeier G

Cancer Res. 2010, 70, 277-287 [PubMed]


Brain ischemic preconditioning does not require PARP-1

Faraco G, Blasi F, Min W, Wang ZQ, Moroni F, Chiarugi A

Stroke. 2010, 41, 181-183 [PubMed]


Mutations in FAM134B, encoding a newly identified Golgi protein, cause severe sensory and autonomic neuropathy

Kurth I, Pamminger T, Hennings JC, Soehendra D, Huebner AK, Rotthier A, Baets J, Senderek J, Topaloglu H, Farrell SA, Nürnberg G, Nürnberg P, De Jonghe P, Gal A, Kaether C, Timmerman V, Hübner CA

Nat Genet. 2009, 41, 1179-1181 [PubMed]


X-chromosomal variation is associated with slow progression to AIDS in HIV-infected women

Siddiqui RA, Sauermann U, Altmüller J, Fritzer E, Nothnagel M, Dalibor N, Fellay J, Kaup FJ, Stahl-Hennig C, Nürnberg P, Krawczak M, Platzer M

Am J Hum Genet. 2009, 85, 228-239 [PubMed]


A highly conserved retinoic acid responsive element controls wt1a expression in the zebrafish pronephros

Bollig F, Perner B, Besenbeck B, Köthe S, Ebert C, Taudien S, Englert C

Development. 2009, 136, 2883-2892 [PubMed]


In vivo phosphoenolpyruvate carboxykinase promoter mapping identifies disrupted hormonal synergism as a target of inflammation during sepsis in mice

Chichelnitskiy E, Vegiopoulos A, Berriel Diaz M, Ziegler A, Kleiman A, Rauch A, Tuckermann J, Herzig S

Hepatology. 2009, 50, 1963-1971 [PubMed]


Polyketide assembly lines of uncultivated sponge symbionts from structure-based gene targeting

Fisch KM, Gurgui C, Heycke N, van der Sar SA, Anderson SA, Webb VL, Taudien S, Platzer M, Rubio BK, Robinson SJ, Crews P, Piel J

Nat Chem Biol. 2009, 5, 494-501 [PubMed]


Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development

Skouloudaki K, Puetz M, Simons M, Courbard JR, Boehlke C, Hartleben B, Engel C, Moeller MJ, Englert C, Bollig F, Schäfer T, Ramachandran H, Mlodzik M, Huber TB, Kuehn EW, Kim E, Kramer-Zucker A, Walz G

Proc Natl Acad Sci USA 2009, 106, 8579-8584 [PubMed]


The PGD2 pathway, independently of FGF9, amplifies SOX9 activity in Sertoli cells during male sexual differentiation

Moniot B, Declosmenil F, Barrionuevo F, Scherer G, Aritake K, Malki S, Marzi L, Cohen-Solal A, Georg I, Klattig J, Englert C, Kim Y, Capel B, Eguchi N, Urade Y, Boizet-Bonhoure B, Poulat F

Development. 2009, 136, 1813-1821 [PubMed]


Systematic evaluation of the effect of common SNPs on pre-mRNA splicing

ElSharawy A, Hundrieser B, Brosch M, Wittig M, Huse K, Platzer M , Rosenstiel P, Schreiber S , Krawczak M , Hampe J

Hum Mutat. 2009, 30, 625-632 [PubMed]


Effects of dietary restriction on mortality and age-related phenotypes in the short-lived fish Nothobranchius furzeri

Terzibasi E, Lefrançois C, Domenici P, Hartmann N, Graf M, Cellerino A

Aging Cell 2009, 8, 88-99 [PubMed]


DNA methylation analysis of chromosome 21 gene promoters at single base pair and single allele resolution

Zhang Y, Rohde C, Tierling S, Jurkowski TP, Bock C, Santacruz D, Ragozin S, Reinhardt R, Groth M, Walter J, Jeltsch A

PLoS Genet 2009, 5, e1000438 [PubMed]


High tandem repeat content in the genome of the short-lived annual fish Nothobranchius furzeri: a new vertebrate model for aging research

Reichwald K, Lauber C, Nanda I, Kirschner J, Hartmann N, Schories S, Gausmann U, Taudien S, Schilhabel MB, Szafranski K, Glöckner G, Schmid M, Cellerino A, Schartl M, Englert C, Platzer M

Genome Biol 2009, 10, R16 [PubMed]


Lymphotoxin β receptor signaling promotes tertiary lymphoid organogenesis in the aorta adventitia of aged ApoE-/- mice

Gräbner R, Lötzer K, Döpping S, Hildner M, Radke D, Beer M, Spanbroek R, Lippert B, Reardon CA, Getz GS, Fu Y-X, Hehlgans T, Mebius RE, van der Wall M, Kruspe D, Englert C, Lovas A, Hu D, Randolph GJ, Weih F, Habenicht AJR

J Exp Med 2009, 206, 233-248 [PubMed]


Selected as "exceptional" by "Faculty of 1000"

A phosphorylation-acetylation switch regulates STAT1 signaling

Krämer OH, Knauer SK, Greiner G, Jandt E, Reichardt S, Gührs KH, Stauber RH, Böhmer FD, Heinzel T

Genes Dev 2009, 23, 223-235 [PubMed]


Critical role of macrophages in glucocorticoid driven vascular calcification in a mouse-model of atherosclerosis

Preusch MR, Rattazzi M, Albrecht C, Merle U, Tuckermann J, Schütz G, Blessing E, Zoppellaro G, Pauletto P, Krempien R, Rosenfeld ME, Katus HA, Bea F

Arterioscler Thromb Vasc Biol 2008, 28, 2158-2164 [PubMed]


The wave property of heavy molecules - Its use in mass spectrometry

Greulich KO

Angew Chem Int Ed Engl 2008, 47, 7990-7991 [PubMed]


Lack of NF-κB2/p100 causes a RelB-dependent block in early B lymphopoiesis

Guo F, Tänzer S, Busslinger M, Weih F

Blood 2008, 112, 551-559 [PubMed]


Paired {beta}-sheet structure of an A{beta}(1-40) amyloid fibril revealed by electron microscopy

Sachse C, Fändrich M, Grigorieff N

Proc Natl Acad Sci U S A 2008, 105, 7462-7466 [PubMed]


SNP and haplotype mapping for genetic analysis in the rat

STAR Consortium, Saar K, Beck A, Bihoreau MT, Birney E, Brocklebank D, Chen Y, Cuppen E, Demonchy S, Dopazo J, Flicek P, Foglio M, Fujiyama A, Gut IG, Gauguier D, Guigo R, Guryev V, Heinig M, Hummel O, Jahn N, Klages S, Kren V, Kube M, Kuhl H, Kuramoto T, Kuroki Y, Lechner D, Lee YA, Lopez-Bigas N, Lathrop GM, Mashimo T, Medina I, Mott R, Patone G, Perrier-Cornet JA, Platzer M, Pravenec M, Reinhardt R, Sakaki Y, Schilhabel M, Schulz H, Serikawa T, Shikhagaie M, Tatsumoto S, Taudien S, Toyoda A, Voigt B, Zelenika D, Zimdahl H, Hubner N

Nat Genet 2008, 40, 560-566 [PubMed]


Widespread and subtle: alternative splicing at short-distance tandem sites

Hiller M, Platzer M

Trends Genet 2008, 24, 246-255 [PubMed]


Opposing effects of dietary protein and sugar regulate a transcriptional target of Drosophila insulin-like peptide signaling

Buch S, Melcher C, Bauer M, Katzenberger J, Pankratz MJ

Cell Metab 2008, 7, 321-332 [PubMed]


Chromatophore genome sequence of paulinella sheds light on acquisition of photosynthesis by eukaryotes

Nowack EC, Melkonian M, Glöckner G

Curr Biol 2008, 18, 410-418 [PubMed]


Dynamics of inner kinetochore assembly and maintenance in living cells

Hemmerich P, Weidtkamp-Peters S, Hoischen C, Schmiedeberg L, Erliandri I, Diekmann S

J Cell Biol 2008, 180, 1101-1114 [PubMed]


Centromere anatomy in the multidrug-resistant pathogen Enterococcus faecium

Derome A, Hoischen C, Bussiek M, Grady R, Adamczyk M, Keedzierska B, Diekmann S, Barillà D, Hayes F

Proc Natl Acad Sci U S A 2008, 105, 2151-2156 [PubMed]


Supreme enLIGHTenment: damage recognition and signaling in the mammalian UV response

Herrlich P, Karin M, Weiss C

Mol Cell 2008, 29, 279-290 [PubMed]


Exploiting the mosaic structure of trans-acyltransferase polyketide synthases for natural product discovery and pathway dissection

Nguyen T, Ishida K, Jenke-Kodama H, Dittmann E, Gurgui C, Hochmuth T, Taudien S, Platzer M, Hertweck C, Piel J

Nat Biotechnol 2008, 26, 225-233 [PubMed]


Reciprocity between phase shifts and amplitude changes in the mammalian circadian clock

Pulivarthy SR, Tanaka N, Welsh DK, De Haro L, Verma IM, Panda S

Proc Natl Acad Sci U S A 2007, 104, 20356-20361 [PubMed]


Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Abeta protofibrils

Habicht G, Haupt C, Friedrich RP, Hortschansky P, Sachse C, Meinhardt J, Wieligmann K, Gellermann GP, Brodhun M, Götz J, Halbhuber K-J, Röcken C, Horn U, Fändrich M

Proc Natl Acad Sci U S A 2007, 104, 19232-19237 [PubMed]

(pdf)


Endogenous transforming growth factor beta1 suppresses inflammation and promotes survival in adult CNS

Makwana M, Jones LL, Cuthill D, Heuer H, Bohatschek M, Hristova M, Friedrichsen S, Ormsby I, Bueringer D, Koppius A, Bauer K, Doetschman T, Raivich G

J Neurosci 2007, 27, 11201-11213 [PubMed]


The TATA-binding protein regulates maternal mRNA degradation and differential zygotic transcription in zebrafish

Ferg M, Sanges R, Gehrig J, Kiss J, Bauer M, Lovas A, Szabo M, Yang L, Straehle U, Pankratz MJ, Olasz F, Stupka E, Müller F

EMBO J 2007, 26, 3945-3956 [PubMed]


Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns

Szafranski K, Schindler S, Taudien S, Hiller M, Huse K, Jahn N, Schreiber S, Backofen R, Platzer M

Genome Biol 2007, 8, R154 [PubMed]


Constitutive alternative NF-κB signaling promotes marginal zone B-cell development but disrupts the marginal sinus and induces HEV-like structures in the spleen

Guo F, Weih D, Meier E, Weih F

Blood 2007, 110, 2381-2389 [PubMed]


Endoplasmic reticulum retention of the gamma-secretase complex component Pen2 by Rer1

Kaether C, Scheuermann J, Fassler M, Zilow S, Shirotani K, Valkova C, Novak B, Kacmar S, Steiner H, Haass C

EMBO Rep 2007, 8, 743-748 [PubMed]

(pdf)


Macrophages and neutrophils are the targets for immune suppression by glucocorticoids in contact allergy

Tuckermann JP, Kleiman A, Moriggl R, Spanbroek R, Neumann A, Illing A, Clausen BE, Stride B, Förster I, Habenicht AJ, Reichardt HM, Tronche F, Schmid W, Schütz G

J Clin Invest 2007, 117, 1381-1390 [PubMed]

Comment in Cell 129, May 18, 2007 (Immunology Select)


Endosymbiont-dependent host reproduction maintains bacterial-fungal mutualism

Partida-Martinez LP, Monajembashi S, Greulich KO, Hertweck C

Curr Biol 2007, 17, 773-777 [PubMed]


Skin inflammation in RelB-/- mice leads to defective immunity and impaired clearance of vaccinia virus

Freyschmidt EJ, Mathias CB, MacArthur DH, Laouar A, Narasimhaswamy M, Weih F, Oettgen HC

J Allergy Clin Immunol 2007, 119, 671-679 [PubMed]


Abnormal thyroid hormone metabolism in mice lacking the monocarboxylate transporter 8

Trajkovic M, Visser TJ, Mittag J, Horn S, Lukas J, Darras VM, Raivich G, Bauer K, Heuer H

J Clin Invest 2007, 117, 627-635 [PubMed]

see also: Editorial in Nature Clinical Practice (July 2007)


Merlin/neurofibromatosis type 2 suppresses growth by inhibiting the activation of ras and rac

Morrison H, Sperka T, Manent J, Giovannini M, Ponta H, Herrlich P

Cancer Res 2007, 67, 520-527 [PubMed]


A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

Hampe J, Franke A, Rosenstiel P, Till A, Teuber M, Huse K, Albrecht M, Mayr G, De La Vega FM, Briggs J, Günther S, Prescott NJ, Onnie CM, Häsler R, Sipos B, Fölsch UR, Lengauer T, Platzer M, Mathew CG

Nat Genet 2007, 39, 2007-2011 [PubMed]


Conditional deletion of Nbs1 in murine cells reveals its role in branching repair pathways of DNA double-strand breaks

Yang YG, Saidi A, Frappart PO, Min W, Barrucand C, Dumon-Jones V, Michelon J, Herceg Z, Wang ZQ

EMBO J 2006, 25, 5527-5538 [PubMed]


SNPSplicer: systematic analysis of SNP-dependent splicing in genotyped cDNAs

ElSharawy A, Manaster C, Teuber M, Rosenstiel P, Kwiatkowski R, Huse K, Platzer M, Becker A, Nürnberg P, Schreiber S, Hampe J

Hum Mutat 2006, 27, 1129-1134 [PubMed]


Sequencing errors or SNPs at splice-acceptor guanines in dbSNP?

Platzer M, Hiller M, Szafranski K, Jahn N, Hampe J, Schreiber S, Backofen R, Huse K

Nat Biotechnol 2006, 24, 1068-1070 [PubMed]


Constraints on the structure of (CUG)97-RNA from MAS solid state NMR spectroscopy

Riedel K, Herbst C, Häfner S, Leppert J, Ohlenschläger O, Swanson MS, Görlach M, Ramachandran R

Angew Chem Int Ed Engl 2006, 45, 5620-5623 [PubMed]


Tumorigenic transformation by CPI-17 through inhibition of a merlin phosphatase

Jin H, Sperka T, Herrlich P, Morrison H

Nature 2006, 442, 576-579 [PubMed]


Antiinflammatory effects of dexamethasone are partly dependent on induction of dual specificity phosphatase 1

Abraham SM, Lawrence T, Kleiman A, Warden P, Medghalchi M, Tuckermann J, Saklatvala J, Clark AR

J Exp Med 2006, 203, 1883-1889 [PubMed]


Phylogenetically widespread alternative splicing at unusual GYNGYN donors

Hiller M, Huse K, Szafranski K, Rosenstiel P, Schreiber S, Backofen R, Platzer M

Genome Biol 2006, 7, R65 [PubMed]

(pdf)


German human methylome project started

Jeltsch A, Walter J, Reinhardt R, Platzer M

Cancer Res 2006, 66, 7378 [PubMed]


Should the draft chimpanzee sequence be finished?

Taudien S, Ebersberger I, Glöckner G, Platzer M

Trends Genet 2006, 22, 122-125 [PubMed]


A short isoform of NOD2/CARD15, NOD2-S, is an endogenous inhibitor of NOD2/receptor-interacting protein kinase 2-induced signaling pathways

Rosenstiel P, Huse K, Till A, Hampe J, Hellmig S, Sina C, Billmann S, von Kampen O, Waetzig GH, Platzer M, Seegert D, Schreiber S

Proc Natl Acad Sci U S A 2006, 103, 3280-3285 [PubMed]

(pdf)


A translational control reporter system (TCRS) for the analysis of translationally controlled processes in the vertebrate cell

Wiesenthal V, Leutz A, Calkhoven CF

Nucleic Acids Res 2006, 34, e23 [PubMed]

(pdf)


 
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