Ausgewählte Publikationen
(letzter 5-Jahres-Impact-Faktor größer 7; in chronologischer Reihenfolge)
RNAi screening uncovers Dhx9 as a modifier of ABT-737 resistance in an Eμ-myc/Bcl-2 mouse model
Mills JR, Malina A, Lee T, Di Paola D, Larsson O, Miething C, Grosse F, Tang H, Zannis-Hadjopoulos M, Lowe SW, Pelletier J
Blood. 2013, 121, 3402-3412 [PubMed]
PPARβ/δ governs Wnt signaling and bone turnover
Scholtysek C, Katzenbeisser J, Fu H, Uderhardt S, Ipseiz N, Stoll C, Zaiss MM, Stock M, Donhauser L, Böhm C, Kleyer A, Hess A, Engelke K, David JP, Djouad F, Tuckermann JP, Desvergne B, Schett G, Krönke G
Nat Med. 2013 (epub ahead of print) [PubMed]
Histone acetyltransferase cofactor trrap maintains self-renewal and restricts differentiation of embryonic stem cells
Sawan C, Hernandez-Vargas H, Murr R, Lopez F, Vaissière T, Ghantous AY, Cuenin C, Imbert J, Wang ZQ, Ren B, Herceg Z
Stem Cells. 2013, 31, 979-991 [PubMed]
Focal segmental glomerulosclerosis is induced by microRNA-193a and its downregulation of WT1
Gebeshuber CA, Kornauth C, Dong L, Sierig R, Seibler J, Reiss M, Tauber S, Bilban M, Wang S, Kain R, Böhmig GA, Moeller MJ, Gröne HJ, Englert C, Martinez J, Kerjaschki D
Nat Med. 2013, 19, 481-487 [PubMed]
Merlin isoform 2 in neurofibromatosis type 2-associated polyneuropathy
Schulz A, Baader SL, Niwa-Kawakita M, Jung MJ, Bauer R, Garcia C, Zoch A, Schacke S, Hagel C, Mautner VF, Hanemann CO, Dun XP, Parkinson DB, Weis J, Schröder JM, Gutmann DH, Giovannini M, Morrison H
Nat Neurosci. 2013, 16, 426-433 [PubMed]
The role of telomeres in stem cells and cancer
Günes C, Rudolph KL
Cell. 2013, 152, 390-393 [PubMed]
Who decides when to cleave an ectodomain?
Hartmann M, Herrlich A, Herrlich P.
Trends Biochem Sci. 2013, 38, 111-120 [PubMed]
Diverging gain-of-function mechanisms of two novel KRAS mutations associated with Noonan and cardio-facio-cutaneous syndromes
Cirstea IC, Gremer L, Dvorsky R, Zhang SC, Piekorz RP, Zenker M, Ahmadian MR
Hum Mol Genet. 2013, 22, 262-270 [PubMed]
Localization and orientation of heavy atom cluster compounds in protein crystals using molecular replacement
Dahms SO, Kuester M, Streb C, Roth C, Sträter N, Than ME
Acta Crystallogr D Biol Crystallogr, 2013, 69, 284-297 [PubMed]
GenColors-based comparative genome databases for small eukaryotic genomes
Felder M, Romualdi A, Petzold A, Platzer M, Sühnel J, Glöckner G
Nucleic Acids Res. 2013, 41, D692-D699 [PubMed]
Competition between NBS1 and ATMIN controls ATM signaling pathway choice
Zhang T, Penicud K, Bruhn C, Loizou JI, Kanu N, Wang ZQ, Behrens A
Cell Rep. 2012, 2, 1498-1504 [PubMed]
Cell-type, dose, and mutation-type specificity dictate mutant p53 functions in vivo
Lee MK, Teoh WW, Phang BH, Tong WM, Wang ZQ, Sabapathy K
Cancer Cell. 2012, 22, 751-764 [PubMed]
The actin nucleator Cobl is crucial for Purkinje cell development and works in close conjunction with the F-actin binding protein Abp1
Haag N, Schwintzer L, Ahuja R, Koch N, Grimm J, Heuer H, Qualmann B, Kessels MM
J Neurosci 2012, 32, 17842-17856 [PubMed]
Functionality, growth and accelerated aging of tissue engineered living autologous vascular grafts
Kelm JM, Emmert MY, Zürcher A, Schmidt D, Begus Nahrmann Y, Rudolph KL, Weber B, Brokopp CE, Frauenfelder T, Leschka S, Odermatt B, Jenni R, Falk V, Zünd G, Hoerstrup SP
Biomaterials. 2012, 33, 8277-8285 [PubMed]
VEGFR-3 is expressed on megakaryocyte precursors in the murine bone marrow and plays a regulatory role in megakaryopoiesis
Thiele W, Krishnan J, Rothley M, Weih D, Plaumann D, Kuch V, Quagliata L, Weich HA, Sleeman JP
Blood. 2012, 120, 1899-1907 [PubMed]
The multiple facets of glucocorticoid action in rheumatoid arthritis
Baschant U, Lane NE, Tuckermann J
Nat Rev Rheumatol. 2012, 8, 645-655 [PubMed]
A physical, genetic and functional sequence assembly of the barley genome
The International Barley Genome Sequencing Consortium
Nature. 2012, 491, 711-716 [PubMed]
PML promotes MHC class II gene expression by stabilizing the class II transactivator
Ulbricht T, Alzrigat M, Horch A, Reuter N, von Mikecz A, Steimle V, Schmitt E, Krämer OH, Stamminger T, Hemmerich P
J Cell Biol. 2012, 199, 49-63 [PubMed]
Genome-wide search for novel human uORFs and N-terminal protein extensions using ribosomal footprinting
Fritsch C, Herrmann A, Nothnagel M, Szafranski K, Huse K, Schumann F, Schreiber S, Platzer M, Krawczak M, Hampe J, Brosch M
Genome Res. 2012, 22, 2208-2218 [PubMed]
UVA-induced DNA double-strand breaks result from the repair of clustered oxidative DNA damages
Greinert R, Volkmer B, Henning S, Breitbart EW, Greulich KO, Cardoso MC, Rapp A
Nucleic Acids Res. 2012, 40, 10263-10273 [PubMed]
Molecular basis of β-amyloid oligomer recognition with a conformational antibody fragment
Morgado I, Wieligmann K, Bereza M, Rönicke R, Meinhardt K, Annamalai K, Baumann M, Wacker J, Hortschansky P, Malesevic M, Parthier C, Mawrin C, Schiene-Fischer C, Reymann KG, Stubbs MT, Balbach J, Görlach M, Horn U, Fändrich M
Proc Natl Acad Sci USA. 2012, 109, 12503-12508 [PubMed]
DNA damage checkpoints in stem cells, ageing and cancer
Sperka T, Wang J, Rudolph KL
Nat Rev Mol Cell Biol. 2012, 13, 579-590 [PubMed]
Cell-cycle-dependent structural transitions in the human CENP-A nucleosome in vivo
Bui M, Dimitriadis EK, Hoischen C, An E, Quénet D, Giebe S, Nita-Lazar A, Diekmann S, Dalal Y
Cell. 2012, 150, 317-326 [PubMed]
Nuclear protein 1 promotes pancreatic cancer development and protects cells from stress by inhibiting apoptosis
Hamidi T, Algül H, Cano CE, Sandi MJ, Molejon MI, Riemann M, Calvo EL, Lomberk G, Dagorn JC, Weih F, Urrutia R, Schmid RM, Iovanna JL
J Clin Invest. 2012, 122, 2092-2103 [PubMed]
The N-terminus of the human RecQL4 helicase is a homeodomain-like DNA interaction motif
Ohlenschläger O, Kuhnert A, Schneider A, Haumann S, Bellstedt P, Keller H, Saluz HP, Hortschansky P, Hänel F, Grosse F, Görlach M, Pospiech H
Nucleic Acids Res. 2012, 40, 8309-8324 [PubMed]
Unusual combinatorial involvement of poly-A/T tracts in organizing genes and chromatin in Dictyostelium
Chang GS, Noegel AA, Mavrich TN, Müller R, Tomsho L, Ward E, Felder M, Jiang C, Eichinger L, Glöckner G, Schuster SC, Pugh BF
Genome Res. 2012, 22, 1098-1106 [PubMed]
Hepatic induction of cholesterol biosynthesis reflects a remote adaptive response to pneumococcal pneumonia
Weber M, Lambeck S, Ding N, Henken S, Kohl M, Deigner HP, Enot DP, Igwe EI, Frappart L, Kiehntopf M, Claus RA, Kamradt T, Weih D, Vodovotz Y, Briles DE, Ogunniyi AD, Paton JC, Maus UA, Bauer M
FASEB J. 2012, 26, 2424-2436 [PubMed]
Transient telomere dysfunction induces chromosomal instability and promotes carcinogenesis
Begus-Nahrmann Y, Hartmann D, Kraus J, Eshraghi P, Scheffold A, Grieb M, Rasche V, Schirmacher P, Lee HW, Kestler HA, Lechel A, Rudolph KL
J Clin Invest. 2012, 122, 2283-2288 [PubMed]
Telomere dysfunctional environment induces loss of quiescence and inherent impairments of hematopoietic stem cell function
Song Z, Zhang J, Ju Z, Rudolph KL
Aging Cell. 2012, 11, 449-455 [PubMed]
Telomere dysfunction puts the brakes on oncogene-induced cancers
Günes C, Rudolph KL
EMBO J. 2012, 31, 2833-2834 [PubMed]
Glucocorticoid receptor dimerization induces MKP1 to protect against TNF-induced inflammation
Vandevyver S, Dejager L, Van Bogaert T, Kleyman A, Liu Y, Tuckermann J, Libert C
J Clin Invest. 2012, 122, 2130-2140 [PubMed]
Disruption of Trp53 in livers of mice induces formation of carcinomas with bilineal differentiation
Katz SF, Lechel A, Obenauf AC, Begus-Nahrmann Y, Kraus JM, Hoffmann EM, Duda J, Eshraghi P, Hartmann D, Liss B, Schirmacher P, Kestler HA, Speicher MR, Rudolph KL
Gastroenterology. 2012, 142, 1229-1239 [PubMed]
Impaired insulin/IGF1 signaling extends life span by promoting mitochondrial L-proline catabolism to induce a transient ROS signal
Zarse K, Schmeisser S, Groth M, Priebe S, Beuster G, Kuhlow D, Guthke R, Platzer M, Kahn CR, Ristow M
Cell Metab. 2012, 15, 451-465 [PubMed]
Increased reprogramming capacity of mouse liver progenitor cells, compared with differentiated liver cells, requires the BAF complex
Kleger A, Mahaddalkar PU, Katz SF, Lechel A, Joo JY, Loya K, Lin Q, Hartmann D, Liebau S, Kraus JM, Cantz T, Kestler HA, Zaehres H, Schöler H, Rudolph KL
Gastroenterology. 2012, 142, 907-917 [PubMed]
Fungal-induced cell cycle impairment, chromosome instability and apoptosis via differential activation of NF-κB
Ben-Abdallah M, Sturny-Leclère A, Avé P, Louise A, Moyrand F, Weih F, Janbon G, Mémet S
PLoS Pathog. 2012, 8, e1002555 [PubMed]
Structurally diverse μ-conotoxin PIIIA isomers block sodium channel NaV1.4
Tietze AA, Tietze D, Ohlenschläger O, Leipold E, Ullrich F, Kühl T, Mischo A, Buntkowsky G, Görlach M, Heinemann SH, Imhof D
Angew Chem Int Ed Engl. 2012, 51, 4058-4061 [PubMed]
A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage
Wang J, Sun Q, Morita Y, Jiang H, Gross A, Lechel A, Hildner K, Guachalla LM, Gompf A, Hartmann D, Schambach A, Wuestefeld T, Dauch D, Schrezenmeier H, Hofmann WK, Nakauchi H, Ju Z, Kestler HA, Zender L, Rudolph KL
Cell. 2012, 148, 1001-1014 [PubMed]
Chitinase enzyme activity in CSF is a powerful biomarker of Alzheimer disease
Watabe-Rudolph M, Song Z, Lausser L, Schnack C, Begus-Nahrmann Y, Scheithauer MO, Rettinger G, Otto M, Tumani H, Thal DR, Attems J, Jellinger KA, Kestler HA, von Arnim CA, Rudolph KL
Neurology. 2012, 78, 569-577 [PubMed]
Disrupted-in-schizophrenia 1 (DISC1) is necessary for the correct migration of cortical interneurons
Steinecke A, Gampe C, Valkova C, Kaether C, Bolz J
J Neurosci 2012, 32, 738-745 [PubMed]
Structural basis of β-amyloid-dependent synaptic dysfunctions
Haupt C, Leppert J, Rönicke R, Meinhardt J, Yadav JK, Ramachandran R, Ohlenschläger O, Reymann KG, Görlach M, Fändrich M.
Angew Chem Int Ed Engl. 2012, 51, 1576-1579 [PubMed]
A distinct response to endogenous DNA damage in the development of Nbs1-deficient cortical neurons
Li R, Yang YG, Gao Y, Wang ZQ, Tong WM
Cell Res. 2012, 22, 859-872 [PubMed]
Mapping of quantitative trait loci controlling lifespan in the short-lived fish Nothobranchius furzeri – a new vertebrate model for age research
Kirschner J, Weber D, Neuschl C, Franke A, Böttger M, Zielke L, Powalsky E, Groth M, Shagin D, Petzold A, Hartmann N, Englert C, Brockmann GA, Platzer M, Cellerino A, Reichwald K
Aging Cell 2012, 11, 252-261 [PubMed]
Adult neurogenesis in the short-lived teleost Nothobranchius furzeri: localization of neurogenic niches, molecular characterization and effects of aging
Tozzini ET, Baumgart M, Battistoni G, Cellerino A
Aging Cell. 2012, 11, 241-251 [PubMed]
Heterozygous mutations causing partial prohormone convertase 1 deficiency contribute to human obesity
Creemers J, Choquet H, Stijnen P, Vatin V, Pigeyre M, Beckers S, Meulemans S, Than ME, Yengo L, Tauber M, Balkau B, Elliott P, Jarvelin M-R, Van Hul W, Van Gaal L, Hoberl F, Pattoul F, Froguel P, Meyre D
Diabetes 2012, 61, 383-390 [PubMed]
Colony-stimulating factor-1 mediates macrophage-related neural damage in a model for Charcot-Marie-Tooth disease type 1X
Groh J, Weis J, Zieger H, Stanley E, Heuer H, Martini R
Brain 2012, 135, 88-104 [PubMed]
Glucocorticoid receptor dimerization is required for survival in septic shock via suppression of interleukin-1 in macrophages
Kleiman A, Hübner S, Rodriguez Parkitna JM, Neumann A, Hofer S, Weigand MA, Bauer M, Schmid W, Schütz G, Libert C, Reichardt HM, Tuckermann JP
FASEB J. 2012, 26, 722-729 [PubMed]
Glucocorticoid therapy of antigen-induced arthritis depends on the dimerized glucocorticoid receptor in T cells
Baschant U, Frappart L, Rauchhaus U, Bruns L, Reichardt HM, Kamradt T, Bräuer R, Tuckermann JP
Proc Natl Acad Sci USA. 2011, 108, 19317-19322 [PubMed]
Evaluated by "Faculty of 1000"MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1Cdc25 pathway
Gruber R, Zhou Z, Sukchev M, Joerss T, Frappart PO, Wang ZQ
Nat Cell Biol. 2011, 13, 1325-1334 [PubMed]
Molecular control of systemic bile acid homeostasis by the liver glucocorticoid receptor
Rose AJ, Díaz MB, Reimann A, Klement J, Walcher T, Krones-Herzig A, Strobel O, Werner J, Peters A, Kleyman A, Tuckermann JP, Vegiopoulos A, Herzig S
Cell Metab. 2011, 14, 123-130 [PubMed]
Requirement for DNA ligase IV during embryonic neuronal development
Gatz SA, Ju L, Gruber R, Hoffmann E, Carr AM, Wang ZQ, Liu C, Jeggo PA
J Neurosci. 2011, 31, 10088-10100 [PubMed]
Phylogeny-wide analysis of social amoeba genomes highlights ancient origins for complex intercellular communication
Heidel AJ, Lawal HM, Felder M, Schilde C, Helps NR, Tunggal B, Rivero F, John U, Schleicher M, Eichinger L, Platzer M, Noegel AA, Schaap P, Glöckner G
Genome Res. 2011, 21, 1882-1891 [PubMed]
Premitotic assembly of human CENPs -T and -W switches centromeric chromatin to a mitotic state
Prendergast L, van Vuuren C, Kaczmarczyk A, Doering V, Hellwig D, Quinn N, Hoischen C, Diekmann S, Sullivan KF
PLoS Biol. 2011, 9, e1001077 [PubMed]
Mitochondrial DNA copy number and function decrease with age in the short-lived fish Nothobranchius furzeri
Hartmann N, Reichwald K, Wittig I, Dröse S, Schmeisser S, Lück C, Hahn C, Graf M, Gausmann U, Terzibasi E, Cellerino A, Ristow M, Brandt U, Platzer M, Englert C
Aging Cell. 2011, 10, 824-831 [PubMed]
RelA and RelB transcription factors in distinct thymocyte populations control lymphotoxin-dependent interleukin-17 production in γδ T cells
Powolny-Budnicka I, Riemann M, Tänzer S, Schmid RM, Hehlgans T, Weih F
Immunity. 2011, 34, 364-374 [PubMed]
Host plant shifts affect a major defense enzyme in Chrysomela lapponica
Kirsch R, Vogel H, Muck A, Reichwald K, Pasteels JM, Boland W
Proc Natl Acad Sci USA 2011, 108, 4897-4901 [PubMed]
Segrosome assembly at the pliable parH centromere
Wu M, Zampini M, Bussiek M, Hoischen C, Diekmann S, Hayes F
Nucleic Acids Res. 2011, 39, 5082-5097 [PubMed]
Revealing the position of the substrate in nickel superoxide dismutase: a model study
Tietze D, Voigt S, Mollenhauer D, Tischler M, Imhof D, Gutmann T, González L, Ohlenschläger O, Breitzke H, Görlach M, Buntkowsky G
Angew Chem Int Ed Engl. 2011, 50, 2946-2950 [PubMed]
Serine 312 phosphorylation is dispensable for wild-type p53 functions in vivo
Lee MK, Tong WM, Wang ZQ, Sabapathy K
Cell Death Differ. 2011, 18, 214-221 [PubMed]
Identification of adult nephron progenitors capable of kidney regeneration in zebrafish
Diep CQ, Ma D, Deo RC, Holm TM, Naylor RW, Arora N, Wingert RA, Bollig F, Djordjevic G, Lichman B, Zhu H, Ikenaga T, Ono F, Englert C, Cowan CA, Hukriede NA, Handin RI, Davidson AJ
Nature 2011, 470, 95-100 [PubMed]
Comparative and functional genomics provide insights into the pathogenicity of dermatophytic fungi
Burmester A*, Shelest E*, Glöckner G*, Heddergott C*, Schindler S, Staib P, Heidel A, Felder M, Petzold A, Szafranski K, Feuermann M, Pedruzzi I, Priebe S, Groth M, Winkler R, Li W, Kniemeyer O, Schroeckh V, Hertweck C, Hube B, White TC, Platzer M, Guthke R, Heitman J, Wöstemeyer J, Zipfel PF, Monod M, Brakhage AA
Genome Biol. 2011, 12, R7 (*equal contribution) [PubMed]
An anti-inflammatory selective glucocorticoid receptor modulator preserves osteoblast differentiation
Rauch A*, Gossye V*, Bracke D, Gevaert E, Jacques P, Van Beneden K, Vandooren B, Rauner M, Hofbauer LC, Haegeman G, Elewaut D, Tuckermann JP**, De Bosscher K**
FASEB J. 2011, 25, 1323-1332. (*,**equal contribution) [PubMed]
Endosymbiotic gene transfer and transcriptional regulation of transferred genes in Paulinella chromatophora
Nowack EC, Vogel H, Groth M, Grossman AR, Melkonian M, Glöckner G
Mol Biol Evol. 2011, 28, 407-422 [PubMed]
Sorting receptor Rer1 controls surface expression of muscle acetylcholine receptors by ER retention of unassembled {alpha}-subunits
Valkova C*, Albrizio M*, Röder IV, Schwake M, Betto R, Rudolf R**, Kaether C**
Proc Natl Acad Sci USA 2011, 108, 621-625 (*,**equal contribution) [PubMed]
Unlocking the barley genome by chromosomal and comparative genomics
Mayer KF, Martis M, Hedley PE, Simková H, Liu H, Morris JA, Steuernagel B, Taudien S, Roessner S, Gundlach H, Kubaláková M, Suchánková P, Murat F, Felder M, Nussbaumer T, Graner A, Salse J, Endo T, Sakai H, Tanaka T, Itoh T, Sato K, Platzer M, Matsumoto T, Scholz U, Dolezel J, Waugh R, Stein N.
Plant Cell. 2011, 23, 1249-1263. [PubMed]
Frequent gene movement and pseudogene evolution is common to the large and complex genomes of wheat, barley, and their relatives
Wicker T, Mayer KF, Gundlach H, Martis M, Steuernagel B, Scholz U, Simková H, Kubaláková M, Choulet F, Taudien S, Platzer M, Feuillet C, Fahima T, Budak H, Dolezel J, Keller B, Stein N
Plant Cell. 2011, 23, 1706-1718 [PubMed]
Tetrameric organization of vertebrate centromeric nucleosomes
Dimitriadis EK, Weber C, Gill RK, Diekmann S, Dalal Y
Proc Natl Acad Sci USA. 2010, 107, 20317-20322 [PubMed]
Proteomic and functional analysis of the mitotic Drosophila centrosome
Müller H, Schmidt D, Steinbrink S, Mirgorodskaya E, Lehmann V, Habermann K, Dreher F, Gustavsson N, Kessler T, Lehrach H, Herwig R, Gobom J, Ploubidou A, Boutros M, Lange BMH
EMBO J 2010, 29, 3344-3357 [PubMed]
Thymus-derived glucocorticoids mediate androgen effects on thymocyte homeostasis
Chen Y, Qiao S, Tuckermann J, Okret S, Jondal M
FASEB J 2010, 24, 5043-5051 [PubMed]
WRN helicase unwinds Okazaki fragment-like hybrids in a reaction stimulated by the human DHX9 helicase
Chakraborty P, Grosse F
Nucleic Acids Res. 2010, 38, 4722-4730 [PubMed]
Merlin inhibits neurite outgrowth in the CNS
Schulz A, Geissler KJ, Kumar S, Leichsenring G, Morrison H*, Baader SL*
J Neurosci 2010, 30, 10177-10186 (*equal contribution) [PubMed]
Highly modular structure and ligand binding by conformational capture in a minimalistic riboswitch
Duchardt-Ferner E, Weigand JE, Ohlenschläger O, Schmidtke SR, Suess B, Wöhnert J
Angew Chem Int Ed Engl 2010, 49, 6216-6219 [PubMed]
ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import
Dormann D, Rodde R, Edbauer D, Bentmann E, Fischer I, Hruscha A, Than ME, Mackenzie IR, Capell A, Schmid B, Neumann M, Haass C
EMBO J 2010, 29, 2841-2857 [PubMed]
EMBO reviewGlucocorticoids suppress bone formation by attenuating osteoblast differentiation via the monomeric glucocorticoid receptor
Rauch A, Seitz S, Baschant, U, Schilling AF, Illing A, Stride B, Kirilov M, Mandic V, Takacz A, Schmidt-Ullrich R, Ostermay S, Schinke T, Spanbroek R, Zaiss M, Angel PE, Lerner UH, David JP, Reichard HM, Amling M, Schütz G, Tuckermann J
Cell Metab 2010, 11, 517-531 [PubMed]
Processing of the NF-κB2 precursor p100 to p52 is critical for RANKL-induced osteoclast differentiation
Maruyama T, Fukushima H, Nakao K, Shin M, Yasuda H, Weih F, Doi T, Aoki K, Alles N, Ohya K, Hosokawa R, Jimi E
J Bone Miner Res 2010, 25, 1058-1067 [PubMed]
Cross talk between stimulated NF-κB and the tumor suppressor p53
Schneider G, Henrich A, Greiner G, Wolf V, Lovas A, Wieczorek M, Wagner T, Reichardt S, von Werder A, Schmid RM, Weih F, Heinzel T, Saur D, Krämer OH
Oncogene. 2010, 29, 2795-2806 [PubMed]
The pivotal role of the alternative NF-κB pathway in maintenance of basal bone homeostasis and osteoclastogenesis
Soysa NS, Alles N, Weih D, Lovas A, Mian AH, Shimokawa H, Yasuda H, Weih F, Jimi E, Ohya K, Aoki K
J Bone Miner Res. 2010, 25, 809-818 [PubMed]
Selected as "exceptional" by "Faculty of 1000"Structure and biochemical analysis of the heparin-induced E1 dimer of the amyloid precursor protein
Dahms SO, Hoefgen S, Roeser D, Schlott B, Gührs KH, Than ME
Proc Natl Acad Sci USA. 2010, 107, 5381-5386 [PubMed]
Wt1 and retinoic acid signaling in the subcoelomic mesenchyme control the development of the pleuropericardial membranes and the sinus horns
Norden J, Grieskamp T, Lausch E, van Wijk B, van den Hoff MJB, Englert C, Petry M, Mommersteeg MTM, Christoffels VM, Niederreither K, Kispert A
Circ Res. 2010, 106, 1212-1220 [PubMed]
Mouse aorta smooth muscle cells differentiate into lymphoid tissue organizer-like cells upon combined TNFR1/LTβR NF-κB signaling
Lötzer K, Döpping S, Connert S, Gräbner R, Spanbroek R, Lemser B, Beer M, Hildner M, Hehlgans T, van der Wall M, Mebius RE, Lovas A, Randolph GJ, Weih F*, Habenicht AJR*
Arterioscler Thromb Vasc Biol. 2010, 30, 395-402 (*equal contribution) [PubMed]
Increased skeletal VEGF enhances β-catenin activity and results in excessively ossified bones
Maes C, Goossens S, Bartunkova S, Drogat B, Coenegrachts L, Stockmans I, Moermans K , Nyabi O, Haigh K , Naessens M, Haenebalcke L, Tuckermann JP, Tjwa M, Carmeliet P, Mandic V, David J-P, Behrens A, Nagy A, Carmeliet G, Haigh JJ
EMBO J. 2010, 29, 424-441 [PubMed]
Mechanism of amyloid plaque formation suggests an intracellular basis of Abeta pathogenicity
Friedrich RP, Tepper K, Rönicke R, Soom M, Westermann M, Reymann K, Kaether C, Fändrich M
Proc Natl Acad Sci USA. 2010, 107, 1942-1947 [PubMed]
Nucleolar retention of a translational C/EBPα isoform stimulates rDNA transcription and cell size
Müller C, Bremer A, Schreiber S, Eichwald S, Calkhoven CF
EMBO J. 2010, 29, 897-909 [PubMed]
C/EBPβΔuORFmice - a genetic model for uORF-mediated translational control in mammals
Wethmar K, Begay V, Smink JJ, Zaragoza K, Wiesenthal V, Dörken B, Calkhoven CF, Leutz A
Genes Dev. 2010, 24, 15-20 [PubMed]
Alpha2-macroglobulin inhibits the malignant properties of astrocytoma cells by impeding beta-catenin signaling
Lindner I, Hemdan NY, Buchold M, Huse K, Bigl M, Oerlecke I, Ricken A, Gaunitz F, Sack U, Naumann A, Hollborn M, Thal D, Gebhardt R, Birkenmeier G
Cancer Res. 2010, 70, 277-287 [PubMed]
Brain ischemic preconditioning does not require PARP-1
Faraco G, Blasi F, Min W, Wang ZQ, Moroni F, Chiarugi A
Stroke. 2010, 41, 181-183 [PubMed]
Mutations in FAM134B, encoding a newly identified Golgi protein, cause severe sensory and autonomic neuropathy
Kurth I, Pamminger T, Hennings JC, Soehendra D, Huebner AK, Rotthier A, Baets J, Senderek J, Topaloglu H, Farrell SA, Nürnberg G, Nürnberg P, De Jonghe P, Gal A, Kaether C, Timmerman V, Hübner CA
Nat Genet. 2009, 41, 1179-1181 [PubMed]
X-chromosomal variation is associated with slow progression to AIDS in HIV-infected women
Siddiqui RA, Sauermann U, Altmüller J, Fritzer E, Nothnagel M, Dalibor N, Fellay J, Kaup FJ, Stahl-Hennig C, Nürnberg P, Krawczak M, Platzer M
Am J Hum Genet. 2009, 85, 228-239 [PubMed]
A highly conserved retinoic acid responsive element controls wt1a expression in the zebrafish pronephros
Bollig F, Perner B, Besenbeck B, Köthe S, Ebert C, Taudien S, Englert C
Development. 2009, 136, 2883-2892 [PubMed]
In vivo phosphoenolpyruvate carboxykinase promoter mapping identifies disrupted hormonal synergism as a target of inflammation during sepsis in mice
Chichelnitskiy E, Vegiopoulos A, Berriel Diaz M, Ziegler A, Kleiman A, Rauch A, Tuckermann J, Herzig S
Hepatology. 2009, 50, 1963-1971 [PubMed]
Polyketide assembly lines of uncultivated sponge symbionts from structure-based gene targeting
Fisch KM, Gurgui C, Heycke N, van der Sar SA, Anderson SA, Webb VL, Taudien S, Platzer M, Rubio BK, Robinson SJ, Crews P, Piel J
Nat Chem Biol. 2009, 5, 494-501 [PubMed]
Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development
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