Publications 2012

 

  • Arias-Cordero E, Ping L, Reichwald K, Delb H, Platzer M, Boland W. Comparative evaluation of the gut microbiota associated with the below- and above-ground life stages (larvae and beetles) of the forest cockchafer, Melolontha hippocastani. PLoS One. 2012, 7, e51557 [PubMed]
  • Asghar A, Groth M, Siol O, Gaube F, Enzensperger C, Glöckner G, Winckler T. Developmental gene regulation by an ancient intercellular communication system in social amoebae. Protist. 2012, 163, 25-37 [PubMed]
  • Baschant U, Lane NE, Tuckermann J. The multiple facets of glucocorticoid action in rheumatoid arthritis. Nat Rev Rheumatol. 2012, 8, 645-655 [PubMed]
  • Baumgart M, Groth M, Priebe S, Appelt J, Guthke R, Platzer M, Cellerino A. Age-dependent regulation of tumor-related miRNAs in the brain of the annual fish Nothobranchius furzeri. Mech Ageing Dev. 2012, 133, 226-233 [PubMed]
  • Begus-Nahrmann Y, Hartmann D, Kraus J, Eshraghi P, Scheffold A, Grieb M, Rasche V, Schirmacher P, Lee HW, Kestler HA, Lechel A, Rudolph KL. Transient telomere dysfunction induces chromosomal instability and promotes carcinogenesis. J Clin Invest. 2012, 122, 2283-2288 [PubMed]
  • Bellstedt P, Herbst C, Häfner S, Leppert J, Görlach M, Ramachandran R. Solid state NMR of proteins at high MAS frequencies: symmetry-based mixing and simultaneous acquisition of chemical shift correlation spectra. J Biomol NMR. 2012, 54, 325-335 [PubMed]
  • Ben-Abdallah M, Sturny-Leclère A, Avé P, Louise A, Moyrand F, Weih F, Janbon G, Mémet S. Fungal-induced cell cycle impairment, chromosome instability and apoptosis via differential activation of NF-κB. PLoS Pathog. 2012, 8, e1002555 [PubMed]
  • Bodemann RR, Rahfeld P, Stock M, Kunert M, Wielsch N, Groth M, Frick S, Boland W, Burse A. Precise RNAi-mediated silencing of metabolically active proteins in the defence secretions of juvenile leaf beetles. Proc Biol Sci. 2012, 279, 4126-4134 [PubMed]
  • Böhm C, Derer A, Axmann R, Hillienhoff U, Zaiss MM, Luther J, Zech C, Stock M, Scholtysek C, Engelke K, Hess A, Tuckermann JP, Schett G, David JP. RSK2 protects mice against TNF-induced bone loss. J Cell Sci. 2012, 125, 2160-2171 [PubMed]
  • Böhm M, Kühl T, Hardes K, Coch R, Arkona C, Schlott B, Steinmetzer T, Imhof D. Synthesis and functional characterization of tridegin and its analogues: inhibitors and substrates of factor XIIIa. ChemMedChem. 2012, 7, 326-333 [PubMed]

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  • Bui M, Dimitriadis EK, Hoischen C, An E, Quénet D, Giebe S, Nita-Lazar A, Diekmann S, Dalal Y. Cell-cycle-dependent structural transitions in the human CENP-A nucleosome in vivo. Cell. 2012, 150, 317-326 [PubMed]
  • Chang GS, Noegel AA, Mavrich TN, Müller R, Tomsho L, Ward E, Felder M, Jiang C, Eichinger L, Glöckner G, Schuster SC, Pugh BF. Unusual combinatorial involvement of poly-A/T tracts in organizing genes and chromatin in Dictyostelium. Genome Res. 2012, 22, 1098-1106 [PubMed]
  • Cockram J, Thiel T, Steuernagel B, Stein N, Taudien S, Bailey PC, O'Sullivan DM. Genome dynamics explain the evolution of flowering time CCT domain gene families in the Poaceae. PLoS One. 2012, 7, e45307 [PubMed]
  • Creemers J, Choquet H, Stijnen P, Vatin V, Pigeyre M, Beckers S, Meulemans S, Than ME, Yengo L, Tauber M, Balkau B, Elliott P, Jarvelin M-R, Van Hul W, Van Gaal L, Hoberl F, Pattoul F, Froguel P, Meyre D. Heterozygous mutations causing partial prohormone convertase 1 deficiency contribute to human obesity. Diabetes 2012, 61, 383-390 [PubMed]
  • D'Angelo L, de Girolamo P, Cellerino A, Tozzini ET, Castaldo L, Lucini C. Neurotrophin Trk receptors in the brain of a teleost fish, Nothobranchius furzeri. Microsc Res Tech. 2012, 75, 81-88 [PubMed]
  • D'Angelo L, De Girolamo P, Cellerino A, Tozzini ET, Varricchio E, Castaldo L, Lucini C. Immunolocalization of S100-like protein in the brain of an emerging model organism: Nothobranchius furzeri. Microsc Res Tech. 2012, 75, 441-447 [PubMed]
  • Dahms SO, Könnig I, Roeser D, Gührs KH, Mayer MC, Kaden D, Multhaup G, Than ME. Metal binding dictates conformation and function of the Amyloid Precursor Protein (APP) E2 domain. J Mol Biol 2012, 416, 438-452 [PubMed]
  • Dambacher S, Deng W, Hahn M, Sadic D, Fröhlich J, Nuber A, Hoischen C, Diekmann S, Leonhardt H, Schotta G. CENP-C facilitates the recruitment of M18BP1 to centromeric chromatin. Nucleus. 2012, 3, 101-110 [PubMed]
  • Dellago H, Khan A, Nussbacher M, Gstraunthaler A, Lämmermann I, Schosserer M, Mück C, Anrather D, Scheffold A, Ammerer G, Jansen-Dürr P, Rudolph KL, Voglauer-Grillari R, Grillari J. ATM-dependent phosphorylation of SNEVhPrp19/hPso4 is involved in extending cellular life span and suppression of apoptosis. Aging (Albany NY). 2012, 4, 290-304 [PubMed]
  • Dey S, Savant S, Teske BF, Hatzoglou M, Calkhoven CF, Wek RC. Transcriptional repression of ATF4 by C/EBPβ differentially regulates the integrated stress response. J Biol Chem. 2012, 287, 21936-21949 [PubMed]

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  • Eskat A, Deng W, Hofmeister A, Rudolphi S, Emmerth S, Hellwig D, Ulbricht T, Döring V, Bancroft JM, McAinsh AD, Cardoso MC, Meraldi P, Hoischen C, Leonhardt H, Diekmann S. Step-wise assembly, maturation and dynamic behavior of the human CENP-P/O/R/Q/U kinetochore sub-complex. PLoS One. 2012, 7, e44717 [PubMed]
  • Fluch S, Kopecky D, Burg K, Simková H, Taudien S, Petzold A, Kubaláková M, Platzer M, Berenyi M, Krainer S, Doležel J, Lelley T. Sequence composition and gene content of the short arm of Rye (Secale cereale) chromosome 1. PLoS One. 2012, 7, e30784 [PubMed]
  • Fritsch C, Herrmann A, Nothnagel M, Szafranski K, Huse K, Schumann F, Schreiber S, Platzer M, Krawczak M, Hampe J, Brosch M. Genome-wide search for novel human uORFs and N-terminal protein extensions using ribosomal footprinting. Genome Res. 2012, 22, 2208-2218 [PubMed]
  • Fuellen G, Dengjel J, Hoeflich A, Hoeijemakers J, Kestler HA, Kowald A, Priebe S, Rebholz-Schuhmann D, Schmeck B, Schmitz U, Stolzing A, Sühnel J, Wuttke D, Vera J. Systems biology and bioinformatics in aging research: a workshop report. Rejuvenation Res. 2012, 15, 631-641 [PubMed]
  • Gao M, Rendtlew Danielsen J, Wei LZ, Zhou DP, Xu Q, Li MM, Wang ZQ, Tong WM, Yang YG. A novel role of human holliday junction resolvase GEN1 in the maintenance of centrosome integrity. PLoS One. 2012, 7, e49687 [PubMed]
  • Geng Y, Monajembashi S, Shao A, Cui D, He W, Chen Z, Hemmerich P, Tang J. Contribution of the C-terminal regions of Promyelocytic leukemia protein (PML) isoform II and V to PML nuclear body formation. J Biol Chem. 2012, 287, 30729-30742 [PubMed]
  • Greinert R, Volkmer B, Henning S, Breitbart EW, Greulich KO, Cardoso MC, Rapp A. UVA-induced DNA double-strand breaks result from the repair of clustered oxidative DNA damages. Nucleic Acids Res. 2012, 40, 10263-10273 [PubMed]
  • Greulich KO, Grigaravicius, Monajembashi S. Single DNA molecule typing, heart beating, DNA repair and ageing: the contribution of fluorescence techniques. Rev Fluor. 2012, 2010, 199-222 [Journal]
  • Greve B, Bölling T, Amler S, Rössler U, Gomolka M, Mayer C, Popanda O, Dreffke K, Rickinger A, Fritz E, Eckardt-Schupp F, Sauerland C, Braselmann H, Sauter W, Illig T, Riesenbeck D, Könemann S, Willich N, Mörtl S, Eich HT, Schmezer P. Evaluation of different biomarkers to predict individual radiosensitivity in an inter-laboratory comparison--lessons for future studies. PLoS One. 2012, 7, e47185 [PubMed]
  • Groh J, Weis J, Zieger H, Stanley E, Heuer H, Martini R. Colony-stimulating factor-1 mediates macrophage-related neural damage in a model for Charcot-Marie-Tooth disease type 1X. Brain 2012, 135, 88-104 [PubMed]

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  • Günes C, Rudolph KL. Telomere dysfunction puts the brakes on oncogene-induced cancers. EMBO J. 2012, 31, 2833-2834 [PubMed]
  • Haag N, Schwintzer L, Ahuja R, Koch N, Grimm J, Heuer H, Qualmann B, Kessels MM. The actin nucleator Cobl is crucial for Purkinje cell development and works in close conjunction with the F-actin binding protein Abp1. J Neurosci 2012, 32, 17842-17856 [PubMed]
  • Haass C, Kaether C, Thinakaran G, Sisodia S. Trafficking and proteolytic processing of APP. Cold Spring Harb Perspect Med. 2012, 2, a006270 [PubMed]
  • Hänold R, Herrmann KH, Schmidt S, Reichenbach JR, Schmidt KF, Löwel S, Witte OW, Weih F, Kretz A. Magnetic resonance imaging of the mouse visual pathway for in vivo studies of degeneration and regeneration in the CNS. Neuroimage 2012, 59, 363-376 [PubMed]
  • Hamidi T, Algül H, Cano CE, Sandi MJ, Molejon MI, Riemann M, Calvo EL, Lomberk G, Dagorn JC, Weih F, Urrutia R, Schmid RM, Iovanna JL. Nuclear protein 1 promotes pancreatic cancer development and protects cells from stress by inhibiting apoptosis. J Clin Invest. 2012, 122, 2092-2103 [PubMed]
  • Hartmann N, Englert C. A microinjection protocol for the generation of transgenic killifish (species: Nothobranchius furzeri). Dev Dyn. 2012, 241, 1133-1141 [PubMed]
  • Haupt C, Leppert J, Rönicke R, Meinhardt J, Yadav JK, Ramachandran R, Ohlenschläger O, Reymann KG, Görlach M, Fändrich M.. Structural basis of β-amyloid-dependent synaptic dysfunctions. Angew Chem Int Ed Engl. 2012, 51, 1576-1579 [PubMed]
  • Herrmann KH, Schmidt S, Kretz A, Hänold R, Krumbein I, Metzler M, Gaser C, Witte OW, Reichenbach JR. Possibilities and limitations for high resolution small animal MRI on a clinical whole-body 3T scanner. MAGMA. 2012, 25, 233-244 [PubMed]
  • Hübner S, Tuckermann J. Molecular mechanisms of the glucocorticoid receptor in steroid therapy – lessons from transgenic mice. Biomolecular Concepts 2012, 3, 241-253
  • Illing A, Liu P, Ostermay S, Schilling A, de Haan G, Krust A, Amling M, Chambon P, Schinke T, Tuckermann JP. Estradiol increases hematopoietic stem and progenitor cells independent on its actions on bone. Haematologica. 2012, 97, 1131-1135 [PubMed]

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  • Jahns F, Wilhelm A, Greulich KO, Mothes H, Radeva M, Wölfert A, Glei M. Impact of butyrate on PKM2 and HSP90β expression in human colon tissues of different transformation stages: a comparison of gene and protein data. Genes Nutr. 2012, 7, 235-246 [PubMed]
  • Kalamarides M, Acosta MT, Babovic-Vuksanovic D, Carpen O, Cichowski K, Evans DG, Giancotti F, Hanemann CO, Ingram D, Lloyd AC, Mayes DA, Messiaen L, Morrison H, North K, Packer R, Pan D, Stemmer-Rachamimov A, Upadhyaya M, Viskochil D, Wallace MR, Hunter-Schaedle K, Ratner N.. Neurofibromatosis 2011: a report of the Children's Tumor Foundation annual meeting.. Acta Neuropathol. 2012, 123, 369-380 [PubMed]
  • Katz SF, Lechel A, Obenauf AC, Begus-Nahrmann Y, Kraus JM, Hoffmann EM, Duda J, Eshraghi P, Hartmann D, Liss B, Schirmacher P, Kestler HA, Speicher MR, Rudolph KL. Disruption of Trp53 in livers of mice induces formation of carcinomas with bilineal differentiation. Gastroenterology. 2012, 142, 1229-1239 [PubMed]
  • Kelm JM, Emmert MY, Zürcher A, Schmidt D, Begus Nahrmann Y, Rudolph KL, Weber B, Brokopp CE, Frauenfelder T, Leschka S, Odermatt B, Jenni R, Falk V, Zünd G, Hoerstrup SP. Functionality, growth and accelerated aging of tissue engineered living autologous vascular grafts. Biomaterials. 2012, 33, 8277-8285 [PubMed]
  • Kirschner J, Weber D, Neuschl C, Franke A, Böttger M, Zielke L, Powalsky E, Groth M, Shagin D, Petzold A, Hartmann N, Englert C, Brockmann GA, Platzer M, Cellerino A, Reichwald K. Mapping of quantitative trait loci controlling lifespan in the short-lived fish Nothobranchius furzeri – a new vertebrate model for age research. Aging Cell 2012, 11, 252-261 [PubMed]
  • Kirshner M, Galron R, Frenkel D, Mandelbaum G, Shiloh Y, Wang ZQ, Barzilai A. Malfunctioning DNA damage response (DDR) leads to the degeneration of nigro-striatal pathway in mouse brain. J Mol Neurosci. 2012, 46, 554-568 [PubMed]
  • Kleger A, Mahaddalkar PU, Katz SF, Lechel A, Joo JY, Loya K, Lin Q, Hartmann D, Liebau S, Kraus JM, Cantz T, Kestler HA, Zaehres H, Schöler H, Rudolph KL. Increased reprogramming capacity of mouse liver progenitor cells, compared with differentiated liver cells, requires the BAF complex. Gastroenterology. 2012, 142, 907-917 [PubMed]
  • Kleiman A, Hübner S, Rodriguez Parkitna JM, Neumann A, Hofer S, Weigand MA, Bauer M, Schmid W, Schütz G, Libert C, Reichardt HM, Tuckermann JP. Glucocorticoid receptor dimerization is required for survival in septic shock via suppression of interleukin-1 in macrophages. FASEB J. 2012, 26, 722-729 [PubMed]
  • Klement K, Melle C, Murzik U, Diekmann S, Norgauer J, Hemmerich P. Accumulation of annexin A5 at the nuclear envelope is a biomarker of cellular aging. Mech Ageing Dev. 2012, 133, 508-522 [PubMed]
  • Kleyer A, Scholtysek C, Bottesch E, Hillienhof U, Beyer C, Distler JH, Tuckermann J, Schett G, Krönke G. Liver X receptors orchestrate osteoblast/osteoclast crosstalk and counteract pathologic bone loss. J Bone Miner Res. 2012, 27, 2442-2451 [PubMed]

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  • Koeberle SC, Romir J, Fischer S, Koeberle A, Schattel V, Albrecht W, Grütter C, Werz O, Rauh D, Stehle T, Laufer SA. Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor. Nat Chem Biol. 2012, 8, 141-143 [PubMed]
  • Kuhnert A, Schmidt U, Monajembashi S, Franke C, Schlott B, Grosse F, Greulich KO, Saluz HP, Hänel F. Proteomic identification of PSF and p54(nrb) as TopBP1-interacting proteins. J Cell Biochem. 2012, 113, 1744-1753 [PubMed]
  • Lee MK, Teoh WW, Phang BH, Tong WM, Wang ZQ, Sabapathy K. Cell-type, dose, and mutation-type specificity dictate mutant p53 functions in vivo. Cancer Cell. 2012, 22, 751-764 [PubMed]
  • Li R, Yang YG, Gao Y, Wang ZQ, Tong WM. A distinct response to endogenous DNA damage in the development of Nbs1-deficient cortical neurons. Cell Res. 2012, 22, 859-872 [PubMed]
  • Lovas A, Weidemann A, Albrecht D, Wiechert L, Weih D, Weih F. p100 Deficiency is insufficient for full activation of the alternative NF-κB pathway: TNF cooperates with p52-RelB in target gene transcription. PLoS One. 2012, 7, e42741 [PubMed]
  • Mameaux S, Cockram J, Thiel T, Steuernagel B, Stein N, Taudien S, Jack P, Werner P, Gray JC, Greenland AJ, Powell W. Molecular, phylogenetic and comparative genomic analysis of the cytokinin oxidase/dehydrogenase gene family in the Poaceae. Plant Biotechnol J. 2012, 10, 67-82 [PubMed]
  • Mayerl S, Visser TJ, Darras VM, Horn S, Heuer H. Impact of Oatp1c1 deficiency on thyroid hormone metabolism and action in the mouse brain. Endocrinology. 2012, 153, 1528-1537 [PubMed]
  • Mischo A, Ohlenschläger O, Gührs KH, Görlach M. Recombinant production of isotope-labeled peptides and spontaneous cyclization of amino-terminal glutamine into pyroglutamic acid. Chembiochem. 2012, 13, 1421-1423 [PubMed]
  • Morgado I, Wieligmann K, Bereza M, Rönicke R, Meinhardt K, Annamalai K, Baumann M, Wacker J, Hortschansky P, Malesevic M, Parthier C, Mawrin C, Schiene-Fischer C, Reymann KG, Stubbs MT, Balbach J, Görlach M, Horn U, Fändrich M. Molecular basis of β-amyloid oligomer recognition with a conformational antibody fragment. Proc Natl Acad Sci USA. 2012, 109, 12503-12508 [PubMed]
  • Müller J, Heuer H. Understanding the hypothalamus-pituitary-thyroid axis in Mct8 deficiency. Eur Thyroid J 2012, 1, 72-79 [Journal]

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  • Mueller KM, Themanns M, Friedbichler K, Kornfeld JW, Esterbauer H, Tuckermann JP, Moriggl R. Hepatic growth hormone and glucocorticoid receptor signaling in body growth, steatosis and metabolic liver cancer development. Mol Cell Endocrinol. 2012, 361, 1-11 [PubMed]
  • Ohlenschläger O, Kuhnert A, Schneider A, Haumann S, Bellstedt P, Keller H, Saluz HP, Hortschansky P, Hänel F, Grosse F, Görlach M, Pospiech H. The N-terminus of the human RecQL4 helicase is a homeodomain-like DNA interaction motif. Nucleic Acids Res. 2012, 40, 8309-8324 [PubMed]
  • Philipps A, Dauber M, Groth M, Schirrmeier H, Platzer M, Krumbholz A, Wutzler P, Zell R. Isolation and molecular characterization of a second serotype of the encephalomyocarditis virus.. Vet Microbiol. 2012, 161, 49-57 [PubMed]
  • Ping L, Platzer M, Wen G, Delaroque N. Coevolution of aah: a dps-like gene with the host bacterium revealed by comparative genomic analysis. Scientific World Journal 2012, 2012, 504905 [PubMed]
  • Rashmi RN, Eckes B, Glöckner G, Groth M, Neumann S, Gloy J, Sellin L, Walz G, Schneider M, Karakesisoglou I, Eichinger L, Noegel AA. The nuclear envelope protein Nesprin-2 has roles in cell proliferation and differentiation during wound healing. Nucleus. 2012, 3, 172-186 [PubMed]
  • Reichardt SD, Föller M, Rexhepaj R, Pathare G, Minnich K, Tuckermann JP, Lang F, Reichardt HM. Glucocorticoids enhance intestinal glucose uptake via the dimerized glucocorticoid receptor in enterocytes. Endocrinology. 2012, 153,1783-1794 [PubMed]
  • Rhein C, Tripal P, Seebahn A, Konrad A, Kramer M, Nagel C, Kemper J, Bode J, Mühle C, Gulbins E, Reichel M, Becker CM, Kornhuber J. Functional implications of novel human acid sphingomyelinase splice variants. PLoS One. 2012, 7, e35467 [PubMed]
  • Schäuble S, Klement K, Marthandan S, Münch S, Heiland I, Schuster S, Hemmerich P, Diekmann S. Quantitative model of cell cycle arrest and cellular senescence in primary human fibroblasts. PLoS One. 2012, 7, e42150 [PubMed]
  • Seitz S, Keller J, Schilling AF, Jeschke A, Marshall RP, Stride BD, Wintermantel T, Beil FT, Amling M, Schütz G, Tuckermann J, Schinke T. Pharmacological estrogen administration causes a FSH-independent osteo-anabolic effect requiring ER alpha in osteoblasts. PLoS One. 2012, 7, e50301 [PubMed]
  • Seo Y, Fukushima H, Maruyama T, Kuroishi KN, Osawa K, Nagano K, Aoki K, Weih F, Doi T, Zhang M, Ohya K, Katagiri T, Hosokawa R, Jimi E. Accumulation of p100, a precursor of NF-κB2, enhances osteoblastic differentiation in vitro and bone formation in vivo in aly/aly mice. Mol Endocrinol. 2012, 26, 414-422 [PubMed]

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  • Song Z, Zhang J, Ju Z, Rudolph KL. Telomere dysfunctional environment induces loss of quiescence and inherent impairments of hematopoietic stem cell function. Aging Cell. 2012, 11, 449-455 [PubMed]
  • Sperka T, Wang J, Rudolph KL. DNA damage checkpoints in stem cells, ageing and cancer. Nat Rev Mol Cell Biol. 2012, 13, 579-590 [PubMed]
  • Sponholz C, Huse K, Kramer M, Giamarellos-Bourboulis EJ, Claus RA, Kern A, Engel C, Kuhnt E, Kiehntopf M, Routsi C, Mylona V, Tsangaris I, Heinemann SH, Reinhart K, Platzer M, Bauer M. Gene polymorphisms in the heme degradation pathway and outcome of severe human sepsis. Shock. 2012, 38, 459-465 [PubMed]
  • Steinecke A, Gampe C, Valkova C, Kaether C, Bolz J. Disrupted-in-schizophrenia 1 (DISC1) is necessary for the correct migration of cortical interneurons. J Neurosci 2012, 32, 738-745 [PubMed]
  • Stengel R, Rivera-Milla E, Sahoo N, Ebert C, Bollig F, Heinemann SH, Schonherr R, Englert C. Kcnh1 voltage-gated potassium channels are essential for early zebrafish development. J Biol Chem. 2012, 287, 35565-35575 [PubMed]
  • Taudien S, Gäbel G, Kuss O, Groth M, Grützmann R, Huse K, Kluttig A, Wolf A, Nothnagel M, Rosenstiel P, Greiser KH, Werdan K, Krawczak M, Pilarsky C, Platzer M. Association studies of the copy-number variable ß-defensin cluster on 8p23.1 in adenocarcinoma and chronic pancreatitis. BMC Res Notes. 2012, 5, 629 [PubMed]
  • The International Barley Genome Sequencing Consortium. A physical, genetic and functional sequence assembly of the barley genome. Nature. 2012, 491, 711-716 [PubMed]
  • Thiele S, Ziegler N, Tsourdi E, De Bosscher K, Tuckermann JP, Hofbauer LC, Rauner M. Selective glucocorticoid receptor modulation maintains bone mineral density in mice. J Bone Miner Res. 2012, 27, 2242-2250 [PubMed]
  • Thiele W, Krishnan J, Rothley M, Weih D, Plaumann D, Kuch V, Quagliata L, Weich HA, Sleeman JP. VEGFR-3 is expressed on megakaryocyte precursors in the murine bone marrow and plays a regulatory role in megakaryopoiesis. Blood. 2012, 120, 1899-1907 [PubMed]
  • Tietze AA, Tietze D, Ohlenschläger O, Leipold E, Ullrich F, Kühl T, Mischo A, Buntkowsky G, Görlach M, Heinemann SH, Imhof D. Structurally diverse μ-conotoxin PIIIA isomers block sodium channel NaV1.4. Angew Chem Int Ed Engl. 2012, 51, 4058-4061 [PubMed]

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  • Tozzini ET, Baumgart M, Battistoni G, Cellerino A. Adult neurogenesis in the short-lived teleost Nothobranchius furzeri: localization of neurogenic niches, molecular characterization and effects of aging. Aging Cell. 2012, 11, 241-251 [PubMed]
  • Tümpel S, Rudolph KL. The role of telomere shortening in somatic stem cells and tissue aging: lessons from telomerase model systems. Ann N Y Acad Sci. 2012, 1266, 28-39 [PubMed]
  • Tuo B, Ju Z, Riederer B, Engelhardt R, Manns MP, Rudolph KL, Seidler U. Telomere shortening is associated with reduced duodenal HCOFormula secretory but normal gastric acid secretory capacity in aging mice. Am J Physiol Gastrointest Liver Physiol. 2012, 303, G1312-G1321 [PubMed]
  • Ulbricht T, Alzrigat M, Horch A, Reuter N, von Mikecz A, Steimle V, Schmitt E, Krämer OH, Stamminger T, Hemmerich P. PML promotes MHC class II gene expression by stabilizing the class II transactivator. J Cell Biol. 2012, 199, 49-63 [PubMed]
  • Vaara M, Itkonen H, Hillukkala T, Liu Z, Nasheuer HP, Schaarschmidt D, Pospiech H, Syväoja JE. Segregation of replicative DNA polymerases during S phase DNA - POLYMERASE ϵ, BUT NOT DNA POLYMERASES α/δ, ARE ASSOCIATED WITH LAMINS THROUGHOUT S PHASE IN HUMAN CELLS. J Biol Chem. 2012, 287, 33327-33338 [PubMed]
  • Vandevyver S, Dejager L, Van Bogaert T, Kleyman A, Liu Y, Tuckermann J, Libert C. Glucocorticoid receptor dimerization induces MKP1 to protect against TNF-induced inflammation. J Clin Invest. 2012, 122, 2130-2140 [PubMed]
  • Wang J, Sun Q, Morita Y, Jiang H, Gross A, Lechel A, Hildner K, Guachalla LM, Gompf A, Hartmann D, Schambach A, Wuestefeld T, Dauch D, Schrezenmeier H, Hofmann WK, Nakauchi H, Ju Z, Kestler HA, Zender L, Rudolph KL. A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage. Cell. 2012, 148, 1001-1014 [PubMed]
  • Watabe-Rudolph M, Song Z, Lausser L, Schnack C, Begus-Nahrmann Y, Scheithauer MO, Rettinger G, Otto M, Tumani H, Thal DR, Attems J, Jellinger KA, Kestler HA, von Arnim CA, Rudolph KL. Chitinase enzyme activity in CSF is a powerful biomarker of Alzheimer disease. Neurology. 2012, 78, 569-577 [PubMed]
  • Watson ML, Baehr LM, Reichardt HM, Tuckermann JP, Bodine SC, Furlow JD. A cell autonomous role for the glucocorticoid receptor in skeletal muscle atrophy induced by systemic glucocorticoid exposure. Am J Physiol Endocrinol Metab. 2012, 302, E1210-E1220 [PubMed]
  • Weber M, Lambeck S, Ding N, Henken S, Kohl M, Deigner HP, Enot DP, Igwe EI, Frappart L, Kiehntopf M, Claus RA, Kamradt T, Weih D, Vodovotz Y, Briles DE, Ogunniyi AD, Paton JC, Maus UA, Bauer M. Hepatic induction of cholesterol biosynthesis reflects a remote adaptive response to pneumococcal pneumonia. FASEB J. 2012, 26, 2424-2436 [PubMed]

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  • Weih F, Gräbner R, Hu D, Beer M, Habenicht AJR. Control of dichotomic innate and adaptive immune responses by artery tertiary lymphoid organs in atherosclerosis. Front. Physio. 2012, 3, 226. doi: 10.3389/fphys.2012.00226
  • Wigelsworth DJ, Ruthel G, Schnell L, Herrlich P, Blonder J, Veenstra TD, Carman RJ, Wilkins TD, Van Nhieu GT, Pauillac S, Gibert M, Sauvonnet N, Stiles BG, Popoff MR, Barth H. CD44 promotes intoxication by the clostridial iota-family toxins. PLoS One 2012, 7, e51356 [PubMed]
  • Wilhelm A, Jahns F, Böcker S, Mothes H, Greulich KO, Glei M.. Culturing explanted colon crypts highly improves viability of primary non-transformed human colon epithelial cells. Toxicol In Vitro. 2012, 26, 133-141 [PubMed]
  • Wos-Oxley M, Bleich A, Oxley AP, Kahl S, Janus L, Smoczek A, Nahrstedt H, Pils M, Taudien S, Platzer M, Hedrich HJ, Medina E, Pieper D. Comparative evaluation of establishing a human gut microbial community within rodent models. Gut Microbes. 2012, 3, 234-249 [PubMed]
  • Zarse K, Schmeisser S, Groth M, Priebe S, Beuster G, Kuhlow D, Guthke R, Platzer M, Kahn CR, Ristow M. Impaired insulin/IGF1 signaling extends life span by promoting mitochondrial L-proline catabolism to induce a transient ROS signal. Cell Metab. 2012, 15, 451-465 [PubMed]
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