Publications 2003

 

  • Afonin S, Glaser RW, Berditchevskaia M, Wadhwani P, Gührs KH, Möllmann U, Perner A, Ulrich AS. 4-fluorophenylglycine as a label for 19F NMR structure analysis of membrane-associated peptides. Chembiochem 2003, 4, 1151-1163. [PubMed]
  • Anand K, Ziebuhr J, Wadhwani P, Mesters JR, Hilgenfeld R. Coronavirus main proteinase (3CLpro) structure: basis for design of anti-SARS drugs. Science 2003, 300, 1763-1767. [PubMed]
  • Appel TR, Makovitzky J. Romhányi's staining methods applied to tissue-isolated amyloid fibrils. Acta Histochem 2003, 105, 371-372. [PubMed]
  • Appel TR, Yehia N, Baumeister U, Hartung H, Kluge R, Ströhl D, Fanghänel E. Electrophilic cyclisation of Bis(4-methoxybenzylthio)acetylene - competition between Ar2-6 and Ar1-5 routes, yielding 1 H-2-Benzothiopyrans or spiro derivatives of cyclohexadienone. Eur J Org Chem 2003, 1, 47-53.
  • Birkenmeier G, Müller R, Huse K, Forberg J, Gläser C, Hedrich H, Nicklisch S, Reichenbach A. Human alpha2-macroglobulin: genotype-phenotype relation. Exp Neurol 2003, 184, 153-161. [PubMed]
  • Böhm KJ, Stracke R, Unger E. Motor proteins and kinesin-based nanoactuatoric devices. Tsitol Genet 2003, 37, 11-21. [PubMed]
  • Brenner S, Prösch S, Schenke-Layland K, Riese U, Gausmann U, Platzer C. cAMP-induced interleukin-10 promoter activation depends on CCAAT/enhancer-binding protein expression and monocytic differentiation. J Biol Chem 2003, 278, 5597-5604. [PubMed]
  • Croucher PJ, Mascheretti S, Hampe J, Huse K, Frenzel H, Stoll M, Lu T, Nikolaus S, Yang SK, Krawczak M, Kim WH, Schreiber S. Haplotype structure and association to Crohn's disease of CARD15 mutations in two ethnically divergent populations. Eur J Hum Genet 2003, 11, 6-16. [PubMed]
  • Demirci FY, Ramser J, White NJ, Rigatti BW, Meindl A, Lewis KF, Wen G, Gorin MB. Refinement of the physical location and the genomic characterization of the CRSP2 (EXLM1) gene on Xp11.4. DNA Seq 2003, 14, 123-127. [PubMed]
  • Diekmann S, Siegmund G, Roecker A, Klemm DO. Regioselective nitrilotriacetic acid-cellulose-nickel-complexes for immobilisation of His6-tag proteins. Cellulose 2003, 10, 53-63.

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  • Drenth J, Dijkstra K, Leppert J, Ohlenschläger O, Haas C. Effect of molecular anisotropy on the nucleation of lysozyme. J Phys Chem B 2003, 107, 4203-4207.
  • Fahlbusch B, Rudeschko O, Schlott B, Henzgen M, Schlenvoigt G, Schubert H, Kinne RW. Further characterization of IgE-binding antigens from guinea pig hair as new members of the lipocalin family. Allergy 2003, 58, 629-634. [PubMed]
  • Fändrich M, Forge V, Buder K, Kittler M, Dobson CM, Diekmann S. Myoglobin forms amyloid fibrils by association of unfolded polypeptide segments. Proc Natl Acad Sci U S A 2003, 100, 15463-15468. [PubMed]
  • Giersiefen H, Hilgenfeld R, Hillisch A. Modern methods of drug discovery: an introduction. EXS 2003, 93, 1-18. [PubMed]
  • Hausmann M, Liebe B, Perner B, Jerratsch M, Greulich KO, Scherthan H. Imaging of human meiotic chromosomes by scanning near-field optical microscopy (SNOM). Micron 2003, 34, 441-447. [PubMed]
  • Hausmann M, Winkler R, Hildenbrand G, Finsterle J, Weisel A, Rapp A, Schmitt E, Janz S, Cremer C. COMBO-FISH: specific labeling of nondenatured chromatin targets by computer-selected DNA oligonucleotide probe combinations. Biotechniques 2003, 35, 564-570, 572-577. [PubMed]
  • Helbig JH, König B, Knospe H, Bubert B, Yu C, Lück CP, Riboldi-Tunnicliffe A, Hilgenfeld R, Jacobs E, Hacker J, Fischer G. The PPIase active site of Legionella pneumophila Mip protein is involved in the infection of eukaryotic host cells. Biol Chem 2003, 384, 125-137. [PubMed]
  • Hettmann T, Anemüller S, Borcherding H, Mathé L, Steinrücke P, Diekmann S. Pseudomonas stutzeri soluble nitrate reductase alphabeta-subunit is a soluble enzyme with a similar electronic structure at the active site as the inner membrane-bound alphabetagamma holoenzyme. FEBS Lett 2003, 534, 143-150. [PubMed]
  • Hettmann T, Siddiqui RA, von Langen J, Frey C, Romo MJ, Diekmann S. Mutagenesis study on the role of a lysine residue highly conserved in formate dehydrogenases and periplasmic nitrate reductases. Biochem Biophys Res Commun 2003, 310, 40-47. [PubMed]
  • Hillisch A, Hilgenfeld R. The role of protein 3D-structures in the drug discovery process. EXS 2003, 93, 157-181. [PubMed]

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  • Isken O, Grassmann CW, Sarisky RT, Kann M, Zhang S, Grosse F, Kao PN, Behrens SE. Members of the NF90/NFAR protein group are involved in the life cycle of a positive-strand RNA virus. EMBO J 2003, 22, 5655-5665. [PubMed]
  • Junker K, Boerner D, Schulze W, Utting M, Schubert J, Werner W. Analysis of genetic alterations in normal bladder urothelium. Urology 2003, 62, 1134-1138. [PubMed]
  • Kaulmann G, Palm GJ, Schilling K, Hilgenfeld R, Wiederanders B. An unfolding/refolding step helps in the crystallization of a poorly soluble protein. Acta Crystallogr D Biol Crystallogr 2003, 59, 1243-1245. [PubMed]
  • Klupsch T, Mühlig P, Hilgenfeld R. The distribution of a macromolecular solute within an evaporating drop: an exact analytical solution. Physicochem Eng Aspects 2003, 231, 85-102.
  • Köhler R, Fanghänel J, König B, Lüneberg E, Frosch M, Rahfeld JU, Hilgenfeld R, Fischer G, Hacker J, Steinert M. Biochemical and functional analyses of the Mip protein: influence of the N-terminal half and of peptidylprolyl isomerase activity on the virulence of Legionella pneumophila. Infect Immun 2003, 71, 4389-4397. [PubMed]
  • Kollmar M, Glöckner G. Identification and phylogenetic analysis of Dictyostelium discoideum kinesin proteins. BMC Genomics 2003, 4, 47. [PubMed]
  • Kronen M, Görls H, Nguyen HH, Reissmann S, Bohl M, Sühnel J, Gräfe U. Crystal structure and conformational analysis of ampullosporin A. J Pept Sci 2003, 9, 729-744. [PubMed]
  • Krumme D, Budde H, Hecht HJ, Menge U, Ohlenschläger O, Ross A, Wissing J, Wray V, Flohé L. NMR studies of the interaction of tryparedoxin with redox-inactive substrate homologues. Biochemistry 2003, 42, 14720-14728. [PubMed]
  • Laurine E, Grégoire C, Fändrich M, Engemann S, Marchal S, Thion L, Mohr M, Monsarrat B, Michel B, Dobson CM, Wanker E, Erard M, Verdier JM. Lithostathine quadruple-helical filaments form proteinase K-resistant deposits in Creutzfeldt-Jakob disease. J Biol Chem 2003, 278, 51770-51778. [PubMed]
  • Leppert J, Heise B, Ohlenschläger O, Görlach M, Ramachandran R. Broadband RFDR with adiabatic inversion pulses. J Biomol NMR 2003, 26, 13-24. [PubMed]

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  • Louit G, Hocquet A, Ghomi M, Meyer M, Sühnel J. Are guanine tetrads stabilised by bifurcated hydrogen bonds? An AIM topological analysis of the electronic density. PhysChemComm 2003, 6, 1-5.
  • Meyer M, Sühnel J. Interaction of cyclic cytosine-, guanine-, thymine-, uracil- and mixed guanine-cytosine base tetrads with K+, Na+ and Li+ ions - a density functional study. J Biomol Struct Dyn 2003, 20, 507-517. [PubMed]
  • Meyer M, Sühnel J. Self-association of isoguanine nucleobases and molecular recognition of alkaline ions: tetrad versus pentad structures. J Phys Chem A 2003, 107, 1025-1031.
  • Mühlig P, Klupsch T, Kaulmann U, Hilgenfeld R. Noninvasive in situ observation of the crystallization kinetics of biological macromolecules by confocal laser scanning microscopy. J Struct Biol 2003, 142, 47-55. [PubMed]
  • Ohlenschläger O, Wöhnert J, Ramachandran R, Sich C, Görlach M. Nuclear magnetic resonance studies of ribonucleic acids. Spectroscopy 2003, 17, 537-547.
  • Palczewska M, Groves P, Batta G, Heise B, Kuznicki J. Calretinin and calbindin D28k have different domain organizations. Protein Sci 2003, 12, 180-184. [PubMed]
  • Pestryakov PE, Weisshart K, Schlott B, Khodyreva SN, Kremmer E, Grosse F, Lavrik OI, Nasheuer HP. Human replication protein A. The C-terminal RPA70 and the central RPA32 domains are involved in the interactions with the 3'-end of a primer-template DNA. J Biol Chem 2003, 278, 17515-17524. [PubMed]
  • Pollok S, Stoepel J, Bauerschmidt C, Kremmer E, Nasheuer HP. Regulation of eukaryotic DNA replication at the initiation step. Biochem Soc Trans 2003, 31, 266-269. [PubMed]
  • Prinz H, Ishii Y, Hirano T, Stoiber T, Camacho Gomez JA, Schmidt P, Düssmann H, Burger AM, Prehn JH, Günther EG, Unger E, Umezawa K. Novel benzylidene-9(10H)-anthracenones as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization. J Med Chem 2003, 46, 3382-3394. [PubMed]
  • Prots I, Stracke R, Unger E, Böhm KJ. Isopolar microtubule arrays as a tool to determine motor protein directionality. Cell Biol Int 2003, 27, 251-253. [PubMed]

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  • Sauter SR, Diekmann S, Braun V. Two-step purification of the outer membrane transporter and activator protein Sh1B from Escherichia coli using internally His6-tagged constructs. J Chromatogr B Analyt Technol Biomed Life Sci 2003, 786, 33-37. [PubMed]
  • Schaeferhenrich A, Sendt W, Scheele J, Kuechler A, Liehr T, Claussen U, Rapp A, Greulich KO, Pool-Zobel BL. Putative colon cancer risk factors damage global DNA and TP 53 in primary human colon cells isolated from surgical samples. Food Chem Toxicol 2003, 41, 655-664. [PubMed]
  • Sharon M, Kessler N, Levy R, Zolla-Pazner S, Görlach M, Anglister J. Alternative conformations of HIV-1 V3 loops mimic beta hairpins in chemokines, suggesting a mechanism for coreceptor selectivity. Structure 2003, 11, 225-236. [PubMed]
  • Smith RW, Nasheuer HP. Initiation of JC virus DNA replication in vitro by human and mouse DNA polymerase alpha-primase. Eur J Biochem 2003, 270, 2030-2037. [PubMed]
  • Se K, Grosse F. p53 stimulates human topoisomerase I activity by modulating its DNA binding. Nucleic Acids Res 2003, 31, 6585-6592. [PubMed]
  • Striebel HM, Birch-Hirschfeld E, Egerer R, Földes-Papp Z. Virus diagnostics on microarrays. Curr Pharm Biotechnol 2003, 4, 401-415. [PubMed]
  • Stübner M, Schellenberg P. Low temperature photodynamics and photochemistry of the chromophore of green fluorescent protein (GFP). J Phys Chem A 2003, 107, 1246-1252.
  • Thier R, Bonacker D, Stoiber T, Böhm KJ, Wang M, Unger E, Bolt HM, Degen G. Interaction of metal salts with cytoskeletal motor protein systems. Toxicol Lett 2003, 140-141, 75-81. [PubMed]
  • Toshkova R, Ivanova E, Toshkov S, Hoischen C. Inhibition of tumor development by Proteus mirabilis VI stable L-form cytoplasmic membranes. Exp Oncol 2003, 25, 124-127.
  • Traitcheva N, Angelova P, Radeva M, Berg H. ELF fields and photooxidation yielding lethal effects on cancer cells. Bioelectomagnetics 2003, 24, 148-150. [PubMed]

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  • Villescas-Diaz G, Zacharias M. Sequence context dependence of tandem guanine:adenine mismatch conformations in RNA: a continuum solvent analysis. Biophys J 2003, 85, 416-425. [PubMed]
  • Wiesehan K, Buder K, Linke RP, Patt S, Stoldt M, Unger E, Schmitt B, Bucci E, Willbold D. Selection of D-amino-acid peptides that bind to Alzheimer's disease amyloid peptide abeta1-42 by mirror image phage display. Chembiochem 2003, 4, 748-753. [PubMed]
  • Wilhelm T, Hänggi P. Power-law distributions resulting from finite resources. Physica A 2003, 329, 499-508.
  • Wilhelm T, Nasheuer HP, Huang S. Physical and functional modularity of the protein network in yeast. Mol Cell Proteomics 2003, 2, 292-298. [PubMed]
  • Winkler R, Perner B, Rapp A, Durm M, Cremer C, Greulich KO, Hausmann M. Labelling quality and chromosome morphology after low temperature FISH analysed by scanning far-field and scanning near-field optical microscopy. J Microsc 2003, 209, 23-33. [PubMed]
  • Wöhnert J, Görlach M, Schwalbe H. Triple resonance experiments for the simultaneous correlation of H6/H5 and exchangeable protons of pyrimidine nucleotides in 13C,15N-labeled RNA applicable to larger RNA molecules. J Biomol NMR 2003, 26, 79-83. [PubMed]
  • Zacharias M. Continuum solvent modelling of non-polar solvation: improvement by separating surface area dependent cavity and dispersion contributions. J Phys Chem A 2003, 107, 3000-3004.
  • Zacharias M. Perspectives of drug design that targets RNA. Curr Med Chem-Anti-Infective Agents. 2003, 2, 161-172.
  • Zacharias M. Protein-protein docking with a reduced protein model accounting for side-chain flexibility. Protein Sci 2003, 12, 1271-1282. [PubMed]
 
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