Konrad J. Böhm  - FLI Jena  :  Full Papers

• Dreblow K., Kalchishkova N., Böhm K.J.: Kinesin passing permanent blockages along its protofilament track. Biochem. Biophys. Res. Commun. 395, 490–495  (2010)
• Prinz H., Böhm K.J., Müller K.: Synthesis of 2,6-aceanthrylenedione, a cyclic vinylog of anthraquinone. J. Org.Chem. 75, 3867-3870 (2010)
• Surkau G., Böhm K.J., Müller K., Prinz H.: Synthesis, antiproliferative activity and inhibition of tubulin polymerization by anthracenone-based oxime derivatives. Eur. J. Med. Chem. 45, 3354-3364 (2010)
• Nickel H.C., Schmidt P., Böhm K.J., Baasner S., Müller K., Gerlach M., Unger E., Günther E.G., Prinz H.: Synthesis, antiproliferative activity and inhibition of tubulin polymerization by 1,5- and 1,8-disubstituted 10H-anthracen-9-ones bearing a 10-benzylidene or 10-(2-oxo-2-phenylethylidene) moiety. Eur. J. Med. Chem. 45, 3420-3438 (2010)
• Dráberová E., Sulimenko V., Sulimenko T., Böhm K.J., Dráber P.: Recovery of tubulin functions after freeze-drying in the presence of trehalose. Anal. Biochem. 397, 67-72 (2010)
• Behrens S., Habicht W., Wenzel W., Böhm K.J.: Deposition of palladium nanoparticles on self-assembled, zinc-induced tubulin macrotubes and sheets. J. Nanosci. Nanotechnol. 9, 6858-6865 (2009)
• Dreblow K., Kalchishkova N., Böhm K.J.: Kinesin bypassing blockages on microtubule rails. Biophys. Rev. Lett.  4, 139-151 (2009)
• Kalchishkova N., Böhm K.J.: On the relevance of the core helix αlpha 6 to kinesin activity generation. Biophys. Rev. Lett. 4, 63-75 (2009)
• Prinz H., Schmidt P., Böhm K.J., Baasner S.,  Müller K, Unger E., Gerlach M., Günther EG: 10-Phenyl-(2-oxo-ethylidene)-9(10H)-anthracenones as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization. J. Med. Chem. 52, 1284–1294 (2009)
• Kalchishkova N., Böhm KJ.: The role of kinesin neck linker and neck in velocity regulation. J. Mol. Biol.  382, 127-135 (2008)
• Böhm K.J.: Kinesin-driven transport in cell-free environment. Cell Biol. Int. 32, 588-590 (2008)
• Habicht W., Behrens S., Böhm K.J., Dinjus E.: FESEM/EDX and AFM assisted characterization of tubulin derivatives used for template-directed metallization. Microscopy and Microanalysis 13, Suppl. S02, 670-671 (2007)
• Zuse A., Schmidt P., Baasner S., Böhm K.J., Müller K., Gerlach M., Günther E.G., Unger E., Prinz H.: Sulfonate derivatives of naphtho[2,3-b]thiophen-4(9H)-one and 9(10H)-anthracenone as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization. J. Med. Chem. 50, 6059-6066 (2007)
• Habicht W., Behrens S., Böhm K.J., Dinjus E.: Imaging of self-assembled tubulin polymorphs used as metallization templates. J. Physics Conf. Series 61, 374–378 (2007)
• Korosoglou G., Behrens S., Bekeredjian R., Hardt S., Hagenmüller M., Dinjus E., Böhm K.J., Unger E., Katus H.A., Kücherer H: The potential of a new stable ultrasound contrast agent for site-specific targeting. An in vitro experiment. Ultrasound Med. Biol. 32, 1473-1478 (2006)
• Zuse A., Schmidt P., Baasner S., Böhm K.J., Müller K., Gerlach M., Günther E.G., Unger E., Prinz H.: 9-Benzylidene-naphtho[2,3-b]thiophen-4-ones as novel antimicrotubule agents - Synthesis, antiproliferative activity and inhibition of tubulin polymerization. J. Med. Chem. 49, 7816-7825 (2006)
• Böhm K.J., Mavromatos N., Michette A., Stracke R., Unger E.: Movement and alignment of microtubules in electric fields and electric-dipole-moment estimates. Electromagn. Biol. Med. 24, 297–308 (2005)
• Böhm K.J. , Beeg J., Meyer zu Hörste G., Stracke R., Unger E.: Kinesin-driven sorting machine on large scale microtubule arrays. IEEE Transactions on Advanced Packaging 28, 571- 576 (2005)
• Unger E., Stracke R., Michette A., Mavramatos N., Tuszynski J., Böhm K.J.: Microtubules in electric fields. In: Coherence and electric fields in biological systems (ed. J. Pokorny) Neoset Praha, pp. 23-25 (2005)
• Bonacker D., Stoiber T., Böhm K.J., Prots I., Wang M., Unger E., Thier R., Bolt H.M., Degen G.H.: Genotoxicity of inorganic lead salts and disturbance of microtubule function. Environ. Mol. Mutagen. 45, 346-353 (2005)
• Bonacker D., Stoiber T., Wang M.-S., Böhm K.J., Prots I., Unger E., Thier R., Bolt H.M., Degen G.H.: Genotoxicity of inorganic mercury salts based on disturbed microtubule function. Arch. Toxicol.  78, 575-583 (2004)
• Unger E., Stracke R., Beeg J., Meyer zur Hörste G., Böhm K.J.: Biomotor-based nanoactuatoric devices for particle transport and molecular sorting. Biomedizinische Technik 49(2), 1024-1025 (2004)
• Stoiber T., Bonacker D., Böhm K.J., Bolt H.M., Thier R., Degen G.H., Unger E.: Disturbed microtubule function and induction of micronuclei by chelate complexes of mercury(II). Mutation Res. 563, 97–106 (2004)
• Böhm K.J., Unger E.: Kinesin and nanoactuators. In: Encyclopedia of Nanoscience and Nanotechnology (ed. H.S. Nalwa) American Scientific Publishers, vol.  4, pp. 345-357 (2004)
• Bonacker D., Stoiber T., Böhm K.J., Unger E., Degen G.H., Thier R., Bolt H.M.: Chromosomal genotoxicity of nitrobenzene and benzonitrile. Arch. Toxicol. 78, 49-57 (2004)
• Böhm K.J., Stracke R., Unger E.: Motor proteins and kinesin-based nanoactuatoric devices. Cytology and Genetics 37, 11-21 (2003)
• Thier R., Bonacker D., Stoiber T., Böhm K.J., Wang M., Unger E., Bolt H.M., Degen G.: Interaction of metal salts with cytoskeletal motor protein systems. Toxicol. Lett.140-141, 75-81 (2003)
• Prots I., Stracke R., Unger E., Böhm K.J.: Isopolar microtubule arrays as a tool to determine motor protein directionality. Cell Biol. Int.27, 251-253 (2003)
• Behrens S., Rahn K., Habicht W., Böhm K.J., Rösner H., Dinjus E., Unger E.: Nanoscale particle arrays induced by highly ordered protein assemblies. Adv. Mat. 14, 1621-1625 (2002)
• Macůrek L., Dráberóva E., Richterová V., Böhm K.J., Dráber P.: Monoclonal antibodies KN-02 and KN-03 against the heavy chain of kinesin. Hybridoma and Hybridomics 21, 457-462 (2002)
• Sulimenko V., Sulimenko T., Poznanovic S., Nechiporuk-Zloy V., Böhm K.J., Macurek L., Unger E., Dráber P.: Association of brain gamma-tubulins with alphabeta-tubulin dimers. Biochem. J. 365, 889–895 (2002)
• Dráberová E., Macůrek L., Richterová V., Böhm K.J., Dráber P.: Monoclonal antibody KN-01 against heavy chain of kinesin. Folia biologica 48, 77-79 (2002)
• Stracke R., Böhm K.J., Wollweber L., Tuszynski J.A., Unger E.: Analysis of the migration behaviour of single microtubules in electric fields. Biochem. Biophys. Res. Commun. 293, 602-609 (2002)
• Unger E., Stracke R., Beeg J., Böhm K.J.: Motorproteinbasierte Nanoaktuatoren: Experimentelle Realisierung, Grenzen und Aussichten der Entwicklung. In: Sensoren im Fokus neuer Anwendungen - Dresdener Beiträge zur Sensorik, Bd. 16 (eds.Baselt J.P., Gerlach G.) w.e.b. Universitätsverlag Dresden, pp. 45-48 (2002)
• Böhm K.J., Stracke R., Mühlig P., Unger E.: Motorprotein-driven unidirectional transport of micrometer-sized cargoes across isopolar microtubule arrays. Nanotechnology 12, 238-244 (2001)
• Böhm K.J., Stracke R., Unger E.: Parallel and cascaded arrangement of bionanoactuatoric units: Orientation of kinesin-mediated force generation in a cell-free system. In: Motility Systems 2001 (ed. R. Blickhan) Shaker Verlag Aachen, pp. 13-17 (2001)
• Böhm K.J., Stracke R., Vater W., Unger E.: Inhibition of kinesin-driven microtubule motility by polyhydroxy compounds. In: Micro- and Nanostructures of Biological Systems (eds. H.-J. Hein, G. Bischoff) Shaker Verlag Aachen, pp. 153-165 (2001)
• Russwurm S., Böhm K.J., Mühlig P., Wiederhold M., König K., Reinhart K.: Lipopolysaccharide induces distinct alterations in the microtubule cytoskeleton of monocytes. Cell Biol. Toxicol.16, 339-346 (2000)
• Stracke R., Böhm K.J., Burgold J., Schacht H.-J., Unger E.: Physical and technical parameters determining the functioning of a kinesin-based cell-free motor system. Nanotechnology 11, 52-56 (2000)
• Gothe G., Böhm K.J., Unger E.: A new species of the genus Rhizoplasma Verworn (1896). Acta Protozoologica 39, 165 - 167 (2000)
• Böhm K.J., Stracke R., Unger E.: Speeding up kinesin-driven microtubule gliding in vitro by variation of cofactor composition and physicochemical parameters. Cell Biol. Int. 24, 335-341 (2000)
• Böhm K.J., Stracke R., Baum M., Zieren M., Unger E.: Effect of temperature on kinesin-driven microtubule gliding and kinesin ATPase activity. FEBS Lett. 466, 59-62 (2000)
• Fritzsche W., Böhm K.J., Unger E., Köhler J.M.: Metallic nanowires created by biopolymer masking. Applied Physics Lett. 75, 2854-2856 (1999)
• Böhm K.J., Russwurm S., Ghaleb N., Reinhart K., Unger E.: Microtubule formation and kinesin-driven microtubule gliding in vitro in the presence of lipopolysaccharide. Cell Biol. Int. 23, 431-437 (1999)
• Fritzsche W., Köhler J.M., Böhm K.J., Unger E., Wagner T., Kirsch R., Mertig M., Pompe W.: Wiring of metallized microtubules by electron beam-induced structuring. Nanotechnology 10, 331-335 (1999)
• Böhm K.J., Stracke R., Unger E.: Biomakromolekulare Motoren in zellfreien Testsystemen. Grundlagen für künftige Entwicklungen in der Nanotechnologie und Medizin. BIOforum 7-8/99, 418-421 (1999)
• Stonãns I., Stonãne E., Russwurm S., Deigner H.P., Böhm K.J., Wiederhold M., Jäger L., Reinhart K.: HepG2 human hepatoma cells express multiple cytokine genes. Cytokine 11, 151-156 (1999)
• Gothe G., Böhm K.J., Unger E.: Ultrastructural details of plasmodial rhizopod Synamoeba arenaria Grell. Acta Protozoologica 38, 49-59 (1999)
• Fritzsche W., Böhm K.J., Unger E., Köhler J.M.: Making electrical contact to single molecules. Nanotechnology 9, 177-183 (1998)
• Böhm K.J., Vater W., Russwurm S. , Reinhart K., Unger E.: Lipopolysaccharide-caused fragmentation of individual microtubules in vitro observed by video-enhanced differential interference contrast microscopy. FEBS Lett. 425, 134-136 (1998)
• Böhm K.J., Stracke R., Unger E.: Factors determining kinesin-driven microtubule motility in vitro. Cell Biol. Int. 21, 854-857 (1997)
• Böhm K.J., Steinmetzer P., Daniel A., Vater W., Baum M., Unger E.: Kinesin-driven microtubule motility in the presence of alkaline-earth metal ions. Indication for calcium ion-dependent motility. Cell Motil. Cytoskel.37, 226-231 (1997)
• Kirsch R., Mertig M., Pompe W., Wahl R., Sadowski G., Böhm K.J., Unger E.: Three-dimensional metallization of microtubules. Thin Solid Films 305, 248-253 (1997)
• Gothe G., Böhm K.J., Unger E.: Different resting stages of the plasmodial rhizopod Reticulomyxa filosa. Acta Protozoologica 36, 23-29 (1997)
• Wolf K.W., Böhm K.J.: Organisation von Mikrotubuli in der Zelle. Biologie in unserer Zeit 27, 87-95 (1997)
• Vater W., Böhm K.J., Unger E.: Tubulin assembly in the presence of calcium ions and taxol: Microtubule bundling and formation of macrotubule-ring complexes. Cell Motil. Cytoskel. 36, 76-83 (1997)
• Böhm K.J., Unger E.: Microtubule-associated proteins as a subject of biotechnological research. Annual Report 1994 of the Institute of Molecular Biotechnology (eds. Schuster P., Wagner H.), pp. 112-116 (1995)
• Apel H., Böhm K.J., Vater W.: Mikrotubulusbildung in vitro. Programm zur quantitativen Erfassung mittels Spektralphotometer. BioTec Heft 3, 24-25 (1995)
• Vater W., Fritzsche W., Schaper A., Böhm K.J., Unger E., Jovin T.M.: Scanning force microscopy of microtubules and polymorphic tubulin assemblies in air and in liquid. J. Cell Science 108, 1063-1069 (1995)
• Vater W., Böhm K.J., Unger E.: Effects of the fluorescence dye DAPI on microtubule structure in vitro: Formation of novel types of tubulin assembly products. Acta Histochem. 94, 54-66 (1993)
• Oertel B., Vater W., Wiederhold E.-M., Schulze W., Baumgart J., Böhm K.J., Jelke E., Tint I.S., Viklicky V., Unger E.: Fluorenone-azomethines, a novel class of microtubule inhibitors that specifically affect cell proliferation. Acta Histochem. 92, 74-86 (1992)
• Böhm K.J., Vater W., Steinmetzer P., Unger E.: Can coated vesicles bind to microtubules? Acta Histochem. Suppl. 41, 65-72 (1992)
• Schmidt R., Böhm K.J., Vater W., Unger E.: Aluminium-induced osteomalacia and encephalopathy - an aberration of the tubulin assembly into microtubules by Al³⁺ ? Prog. Histochem. Cytochem. 23, 355-364 (1991)
• Schulze W., Gutsche W., Vater W., Oertel B., Böhm K.J., Unger E., Werner W.: Influence of 1,4-benzoquinone derivatives and azomethines on microtubule formation in vitro and experimental leukemias. Pharmazie 45, 686-687 (1990)
• Vater W., Böhm K.J., Steinmetzer P., Unger E.: Determination of the protofilament number in microtubules by templates. Acta Histochem. Suppl. 39, 347-355 (1990)
• Böhm K.J., Vater W., Steinmetzer P., Kusnetsov S.A., Rodionov V.I., Gelfand V.I., Unger E.: Effect of MAP 1, MAP 2, and tau-proteins on structural parameters of tubulin assemblies. Acta Histochem. Suppl. 39, 357-364 (1990)
• Böhm K.J., Vater W., Steinmetzer P., Unger E.: Effect of sodium chloride on the structure of tubulin assemblies. Acta Histochem. Suppl. 39, 365-371 (1990)
• Müller H., Böhm K.J., Vater W., Unger E.: Structural changes within mixed populations of microtubules and protofilament ribbons caused by dilution and cold incubation. Acta Histochem. Suppl. 39, 373-378 (1990)
• Steinmetzer P., Böhm K.J., Vater W., Unger E.: Structural comparison of assemblies from brain microtubule proteins of different vertebrates. Acta Histochem. Suppl. 39, 379-383 (1990)
• Böhm K.J., Vater W., Steinmetzer P., Unger E.: Nucleation of macrotubules on double-walled microtubule seeds. Eur. J. Cell Biol. 51, 33-37 (1990)
• Draber P., Vater W., Böhm K.J., Kuklova E., Unger E.: Inhibition of microtubule assembly in vitro by anti-tubulin monoclonal antibodies. FEBS Lett. 262, 209-211 (1990)
• Unger E., Böhm K.J., Vater W.: Structural diversity and dynamics of microtubules and polymorphic tubulin assemblies. Electron Microsc. Rev. 3 355-395 (1990)
• Unger E., Böhm K.J., Müller H., Grossmann H., Fenske H., Vater W.: Formation of double-walled microtubules and multilayered tubulin sheets by basic proteins. Eur. J. Cell Biol. 46, 98-104 (1988)
• Jelke E., Oertel B., Böhm K.J., Unger E.: Tubular cytoskeletal elements in sporangia and zoospores of Phytophthora infestans (Mont.) De Bary (Oomycetes, Pythiaceae). J. Basic Microbiol. 27, 11-21 (1987)
• Böhm K.J., Vater W., Steinmetzer P., Unger E.: Structural dynamics within mixed populations of microtubules and protofilament ribbons. Biochim. Biophys. Acta 929, 154-163 (1987).
• Vater W., Böhm K.J., Unger E.: The protofilament number of microtubules is not influenced by Ca²⁺. Studia biophysica 122, 191-194 (1987)
• Vater W., Böhm K.J., Unger E.: A simple method to obtain microtubule protein poor in microtubule-associated proteins. Acta Histochem. Suppl. 33, 123-129 (1986)
• Unger E., Böhm K.J., Vater W.: Factors regulating microtubule structure. A minireview. Acta Histochem. Suppl. 33, 85-94 (1986)
• Böhm K.J., Unger E., Vater W.: Zur Struktur von Mikrotubuli. Wiss. Z. FSU Jena 36, 144-146 (1986)
• Müller H., Schmidt R., Vater W., Böhm K.J., Unger E.: Strukturelle Veränderungen von Zn2+-induzierten Sheets aus mikrotubulärem Protein nach Einwirkung von Histon H1. Wiss. Z. FSU Jena 36, 147 (1986)
• Vater W., Böhm K.J., Müller H., Unger E.: Turbidometrische Untersuchungen zur Assemblierung mikrotubulären Proteins aus Schweinehirn in vitro: Einfluß von Mikrotubulus-assoziierten Proteinen und von DNA. Wiss. Z. FSU Jena 36, 148-151 (1986)
• Unger E., Böhm K.J., Wondraczek H., Vater W.: Properties of microtubules stabilized by glycerol: cold resistence, influence of Mg2+ and heavier alkaline earth ions. Adv. Biosci. 3, 25-44 (1984) [link to full pdf version]
• Böhm K.J., Vater W., Fenske H., Unger E.: Effect of microtubule-associated proteins on the protofilament number of microtubules assembled in vitro. Biochim. Biophys. Acta 800, 119-126 (1984)
• Böhm K.J., Unger E.: Multiple forms of non-specific acid phosphomonoesterase in Saccharomyces cerevisiae. Biol. Zentralblatt 102, 49-63 (1983)
• Vater W., Böhm K.J., Unger E.: Effects of DNA on the taxol-stimulated in vitro assembly of microtubule protein from porcine brain. Studia biophysica 97, 49-60 (1983)
• Böhm K.J.: Gefrier-Ultramikrotomie: Entwicklungsstand und Anwendungsmöglichkeiten (Mit Beispielen aus der Hefecytologie).  Acta Histochem. 66, 59-84 (1980)
• Böhm K.J., Unger E.: Ultracytochemical characterization of acid phosphatase activities in Saccharomyces cerevisiae. Z. Allg. Mikrobiol. 19, 455-465 (1979)
• Böhm K.J., Unger E.: Ultrathin frozen sections of yeast without aldehyde fixation. In: Electron Microscopy 1978, Volume II (Sturgess J.M., Kalnins V.I., Ottensmeyer F.P., Simon G.T., eds.), Microscopical Society of Canada, Toronto 1978, pp. 58-59
• Böhm K.J., Unger E.: Darstellung von Kristallstrukturen nach Cryo-Ultramikrotomie in Protoplasten von Saccharomyces carlsbergensis. Cytobiologie 15, 159-168 (1977)

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