Bioinformatics


What's Bioinformatics ? I Biological Basics I Databases I Tools I Books I Do you know ... ?

Bioinformatics Tools

There are so many different bioinformatics tools available that it is impossible to list them all. Here you find a small collection of interesting platforms in the life science area.
 
NCBI - National Center for Biotechnology Information (USA)
  Entrez
 
  • life sciences search engine (literature + biological data)
  PubMed
 
  • search service of the National Library of Medicine
  • over 9 million entries in MEDLINE + online journals and data bases
    PubMed Central
   
  • archive of life sciences journals
  BLAST (Basic Local Alignment Search Tool)
 
  • programs for classification and finding of potential homologous ones for a given sequence
  OMIM (Online Mendelian Inheritance in Man)
 
  • data base of human genes + genetically caused diseases
  Taxonomy
 
  • data bases with common and scientific names of organisms with sequence information
EBI - European Bioinformatics Institute (UK)
  EMBL (nucleotide sequence database)
 
  • nucleotide sequences of different species
  • daily data exchange with the GenBank (USA) and the DNA database DDBJ (Japan)
    TrEMBL
   
  • translated nucleotide sequences, annotation "per computer"
  SWISS-PROT (protein sequence database)
 
  • non-redundant, annotations "per hand", cross references to other data bases
  • includes also protein sequences from translated DNA or RNA sequences
PDB (Protein Data Bank)
  • collection of all known, publicly accessible 3D-structures (proteins, protein and nucleotide sequences, + complexes)
  • structures from NMR- and x-ray structure analysis
KEGG - Kyoto Encyclopedia of Genes and Genomes (Japan)
  LIGAND
 
  • chemical database 'universe of chemical reactions'
  • combined search for enzymes and metabolic substances
  BRITE (Biomolecular Relations in Information Transmission and Expression)
 
  • database of binary relations for network computation and logical reasoning involving genes, proteins, and other biological molecules


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